目的 对比全飞秒激光小切口角膜微透镜取出术(SMILE)与半飞秒激光制瓣联合准分子激光(FS-LASIK)两种手术方式 治疗近视及散光术后的干眼情况。方法 选取2017年9月-2018年9月我院近视中心行激光治疗近视的患者68例，分为 SMILE组及FA-LASIK组，两组患者分别进行相应的激光治疗近视手术，进行为期6个月的随访，比较两组手术术后的 泪膜破裂时间(TBUT)及泪液分泌量(Schirmer I试验)。结果 结果显示，两组患者术后早期的泪液分泌情况与泪膜 破裂时间均比术前显著下降，随时间延长有逐步恢复的迹象。而FS-LAISK的TBUT及泪液分泌情况均显著低于SMILE 组，两者间有显著差异(P＜0.05)。结论 SMILE手术与FS-LASIK相比，对术后干眼影响更小。

Objective To compare the dry eye situations after femtosecond laser small incision lenticule extraction(SMILE) and femtosecond laser in situ keratomileusis(FS-LASKI) for myopia. Methods 68 myopic patients in our hospital from September 2017 to September 2018 were selected and divided into SMILE group(38 cases) and FS-LASIK(30 cases). SMILE group was underwent SMILE surgery while FS-LASIK group was underwent FS-LASIK surgery. The tearbreak-up-test(TBUT) and Schirmer I test at 1-month, 3-month and 6-month after surgery were compared between the two group. Results The results that TBUT and Schirmer I test were both significantly lower than preoperative levels in both groups and recovered over time. Both of them recovered faster in SMILE group than in FS-LASIK group and the difference is significant(P<0.05). Conclusion SMILE surgery is better than FS-LASIK surgery in the matter of dry eye.