目的 分析对急性上消化道出血患者应用生长抑素与艾司奥美拉唑钠联合治疗的临床疗效的影响情况。方法 将 2016年8月-2017年10月期间我院收治的98例急性上消化道出血患者作为研究对象，采用随机数字表法分为对照组 (生长抑素治疗)和观察组(生长抑素与艾司奥美拉唑钠联合治疗)，每组患者49例。对比治疗后患者的临床疗效 情况。结果 经治疗后，观察组患者的Blatchford评分(4.88±0.79)分、止血时间(24.51±5.29)h以及住院天数 (9.98±1.99)d明显优于对照组患者的Blatchford评分(6.55±0.45)分、止血时间(31.82±5.55)h以及住院天数 (13.24±2.19)d；观察组患者各血常规及凝血指标显著高于对照组患者的，差异均具有统计学意义(P＜0.05)。结 论 对于急性上消化道出血患者，应用生长抑素与艾司奥美拉唑钠联合治疗，可及时止血，并有效消除炎症，提高 临床疗效。

Objective To investigate the clinical effect of somatostatin combined with Esomeprazole sodium in the treatment of acute upper gastrointestinal hemorrhage. Methods 98 cases with acute upper gastrointestinal hemorrhage in our hospital from August 2016 to October 2017 were selected as the study objects, they were randomly divided into the control group (somatostatin treatment) and the observation group (somatostatin combined with Esomeprazole sodium treatment), 49 cases in each group. Compare the clinical effect of the two groups. Results After treatment, Blatchford score, hemostasis time and hospital stay of the observation group [(4.88±0.79), (24.51±5.29)h, (9.98±1.99) d] were significantly better than those of the control group [(6.55±0.45), (31.82±5.55)h, (13.24±2.19)d], routine blood indexes and coagulation indexes of the observation group were significantly higher than those of the control group, the difference was statistic significant (P<0.05). Conclusion The application of somatostatin combined with Esomeprazole sodium in the treatment of acute upper gastrointestinal hemorrhage can stop the bleeding in time, reduce inflammation effectively, and improve the clinical effect.