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PSCI患者应用言语听觉反馈训练治疗的效果观察

作者:平明亮

所属单位:河南省郑州市第十人民医院康复医学科 (河南 郑州 450000)

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摘要

目的 研究言语听觉反馈训练治疗脑卒中后认知障碍(PSCI)患者临床效果以及对患者血清尿酸(UA)、神经元特异性 烯醇化酶(NSE)水平和认知功能的影响。方法 将64例PSCI患者随机均分为观察组(基础治疗+常规康复训练+言语听 觉反馈训练)和对照组(基础治疗+常规康复训练),比较两组治疗效果。结果 治疗后,两组MoCA各领域评分及总分 均明显升高(P<0.05),两组血清UA、NSE水平明显降低(P<0.05),BI评分明显升高(P<0.05),且观察组变化幅度更 大(P<0.05)。结论 Forbrain言语听觉反馈训练治疗PSCI患者可降低患者血清UA和NSE水平,减轻神经细胞损伤,改 善患者认知功能,促进患者康复。

Objective To study the clinical effects of speech auditory feedback training in patients with post-stroke cognitive impairment (PSCI) and its influence on levels of serum uric acid (UA) and neuron-specific enolase (NSE) and cognitive function. Methods 64 cases of patients with PSCI were randomly divided into observation group (basic treatment and routine rehabilitation training, speech auditory feedback training) and control group (basic treatment and routine rehabilitation training). The treatment effects were compared between the two groups. Results After treatment, the fields scores and total score of MoCA scale in the two groups were significantly increased (P<0.05) while the levels of serum UA and NSE in the two groups were significantly decreased (P<0.05), and the BI scores were significantly increased (P<0.05), and the changes were larger in observation group (P<0.05). Conclusion Forbrain speech auditory feedback training in patients with PSCI can reduce serum UA and NSE levels, reduce nerve cell damage, improve cognitive function and promote patients rehabilitation.

【关键词】脑卒中后认知障碍;言语听觉反馈训练;认知功能;尿酸;神经元特异性烯醇化酶

【中图分类号】R493

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2018.06.003

前言

脑卒中患者常伴随一定程度神经功能损伤,引 起认知障碍等各种并发症和后遗症,不仅降低患者 自理能力和生活质量,还可能直接导致患者再次发 病风险增加和病死率升高[1]。因此,积极改善脑卒中 后认知障碍(Post stroke cognitive impairment, PSCI)患者神经功能,恢复其自主活动能力具有重要 意义,目前临床主要综合各种训练方法进行康复干预 并取得良好效果[2]。言语听觉反馈训练是集视觉、听 觉、思维、言语为一体的训练系统,可有效恢复患 者认知功能[3]。本文主要研究言语听觉反馈训练治疗 PSCI患者临床效果以及对患者认知功能、尿酸(uric acid,UA)和神经元特异性烯醇化酶(neuronspecific enolase,NSE)的影响。