摘要
目的 针对阿司匹林联合氯吡格雷治疗老年冠心病患者中的治疗效果进行分析。方法 选取我院收治的100例老年冠 心病患者,按随机法分为观察组和对照组2组,每组各50例。在基础治疗上,对照组老年冠心病患者给予阿司匹林 治疗,观察组老年冠心病患者在对照组的基础上给予氯吡格雷治疗,比较2组患者的治疗效果和治疗过程中发生不 良反应的情况。结果 观察组患者总有效率为96.00%,对照组患者总有效率为70.00%,2组老年冠心病患者的效率比 较差别明显(P<0.05);观察组患者治疗过程中发生的不良反应为8.00%,对照组患者治疗过程中发生的不良反应为 20.00%,观察组患者的不良反应低于对照组患者的不良反应(P<0.05)。结论 采用阿司匹林、氯吡格雷联合使用治 疗老年冠心病的治疗效果和不良反应明显优于单用阿司匹林,值得在临床推广使用。
Objective To investigate the treatment effect of aspirin combined with clopidogrel in senile patients with coronary heart disease. Methods 100 senile patients with coronary heart disease in our hospital were selected and randomly divided into the observation group and the control group, 50 cases in each group. On the basis of routine treatment, the control group was given aspirin treatment, and the observation group was given clopidogrel on basis of the control group, treatment effect, adverse reactions condition during the process of treatment of the two groups were compared. Results Total efficiency of the observation group and the control group were 96.00%, 70.00%, the difference of efficiency between the two groups had statistic significance (P<0.05), adverse reaction rate during the treatment of the observation group (8.00%) was lower than that of the control group (20.00%) (P<0.05). Conclusion The application of aspirin combined with clopidogrel in treatment of coronary heart disease has better treatment effect and less adverse reaction than aspirin alone, it is worthy of clinical promotion.
【关键词】阿司匹林;氯吡格雷;老年冠心病
【中图分类号】R541.4
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2018.06.007
前言
冠心病是指冠状动脉血管发生动脉粥样硬化病变 而引起血管腔狭窄或阻塞,造成心肌缺血、缺氧、坏 死而导致的心脏病。冠心病的范围较为广泛,还包括 炎症、栓塞等导致管腔狭窄或闭塞[1]。老年病人时常 伴有心绞痛,血管严重阻塞的患者有可能发生心梗, 对病人的生命安全造成威胁。本研究采用阿司匹林联 合氯吡格雷治疗老年冠心病取得了良好的效果,现报 道如下。
罕少疾病杂志
第25卷, 第 6 期
2019年11月

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