目的 比较输尿管中、下段结石患者采用输尿管镜下钬激光碎石术与微创腹腔镜下输尿管切开取石术的临床疗效。 方法 择取2015年1月至2016年12月于我院进行择期手术的88例输尿管中、下段结石患者作为研究对象，采用随机 数字作为分组原则将其分为对照组(44例，行腹腔镜下输尿管切开取石术)与研究组(44例，行输尿管镜下钬激光碎 石术)。结果 研究组手术时间、出血量及住院时间低于对照组(P<0.05)；两组术后即刻结石清除率及6个月后结石 复发率对比差异无统计学意义(P>0.05)。结论 输尿管镜下钬激光碎石术与腹腔镜下输尿管切开取石术治疗输尿管 中、下段结石的效果相当，但前者在手术时间、出血量及术后恢复方面更具优势，更适于临床推广。

Objective To investigate the clinical effect of ureteroscopic holmium laser lithotripsy and laparoscopic ureterolithotomy on treatment of middle and lower ureteral calculi. Methods 88 cases with middle and lower ureteral calculi in our hospital from January 2015 to December 2016 were selected and randomly divided into the control group (44 cases, given laparoscopic ureterolithotomy) and the observation group (44 cases, given ureteroscopic holmium laser lithotripsy). Results Operation time, blood loss of the observation group were lower than those of the control group (P<0.05), the difference of stone-free rate and calculus recurrence rate after 6 months between the two groups had no statistic significance (P>0.05). Conclusion Ureteroscopic holmium laser lithotripsy and laparoscopic ureterotomy have similar effect on treatment of middle and lower ureteral calculi, but the former is better on operation time, blood loss and postoperative recovery, it is more suitable for clinical promotion.