摘要
目的 探讨生长抑制剂配合急诊手术治疗急性胆囊炎的疗效分析。方法 收集我院2014年9月-2016年9月收治的150例 急性胆囊炎患者,随机分为观察组和对照组各75例,对照组予以急诊手术治疗;观察组在对照组的基础上加用生 长抑制剂治疗,比较两组疗效。结果 观察组因术中炎性组织粘连较重而转开腹手术者1例(1.33%),对照组因局部 组织炎性渗出和水肿程度较重转开腹手术者12例(16.0%);观察组术后炎性指标水平均低于对照组(P<0.05);观察 组术后发热、恶心呕吐、腹痛等临床症状恢复时间均短于对照组,差异有统计学意义(P<0.05);观察组术后不良 反应总发生率(17.3%)明显低于对照组(34.7%),差异具有统计学意义(P<0.05)。结论 生长抑制剂能减少胆汁的分 泌,减轻炎性反应,减轻病灶周围组织渗出、水肿、粘连,能提高急诊手术的成功率,减少手术并发症的发生,促 进患者尽快恢复。
Objective To investigate the efficacy of growth inhibitor combined with emergency surgery in the treatment of acute cholecystitis. Methods 150 patients with acute cholecystitis treated in our hospital from September 2014 to September 2016 were randomly divided into observation group (75 cases) and control group (75 cases). Both groups were given emergency surgical treatment; besides, the observation group was given additional growth inhibitor, the efficacies of the two groups were compared. Results In the observation group, 1 case (1.33%) was converted to open surgery due to severe inflammatory tissue adhesion during operation, 12 cases (16.0%) were converted to open surgery due to severe inflammatory exudation and edema in the control group. The inflammatory index level of the observation group was lower than that of the control group (P<0.05). The recovery time of clinical symptoms such as fever, nausea vomiting and abdominal pain in the observation group was shorter than that in the control group(P<0.05). The total incidence of postoperative adverse reactions in the observation group (17.3%) was significantly lower than that in the control group (34.7%)(P<0.05). Conclusion Growth inhibitor can reduce bile secretion, inflammatory reaction, exudation, edema and adhesion around lesions, improve the success rate of emergency surgery, reduce the incidence of surgical complications and promote the recovery of patients as soon as possible.
【关键词】生长抑制剂;急诊手术;急性胆囊炎;疗效
【中图分类号】R657.41
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2018.06.010
前言
急性胆囊炎是外科常见急腹症之一,主要表现为 发热、恶心、呕吐、右上腹阵发性绞痛,大多数患者 病症轻微,经内科胃肠减压、解痉止痛和抗感染治疗 后可好转[1]。部分患者保守治疗无效,或者病情较严 重,胆囊有坏疽、穿孔迹象者需行急诊手术切除胆 囊,清除胆囊周围炎性坏死组织,避免急性胆囊炎严 重并发症的发生[2]。但是由于急性期,胆囊炎症水肿 和组织粘连较严重,手术野解剖结构不清晰,手术 难度较大,易损伤周围血管和神经,产生一系列手术并发症[3]。生长抑制剂可以抑制炎症反应和多种消化 酶、消化液的分泌,能减轻组织水肿和胃肠减压量, 被广泛应用于治疗急性胰腺炎[4]。本研究在急诊手术 的基础上配合使用生长抑制剂治疗75例急性胆囊炎患 者,观察其临床疗效,现将结果报道如下。
罕少疾病杂志
第25卷, 第 6 期
2019年11月
相关文章