目的 总结我院经食管超声心动图(TEE)引导下房间隔缺损(ASD)经皮导管介入封堵术的围术期护理经验。方法 入选 2015年11月至2017年4月我院应用TEE引导下经皮导管介入封堵技术治疗ASD患者26例，从术中TEE操作护理、手术封 堵器械无菌操作配合和术中相关并发症指标观测三个方面制定护理操作规范，术中严格执行，总结分析护理成效。 结果 在TEE操作过程中1例患者出现口咽部黏膜水肿，无破损出血，所有患者未出现牙齿松动脱落；术中没有出现 导丝污染情况；术中监测及时发现1例患者在导丝输送过程中出现频发房性早搏，与术者配合调整导丝方向后恢复 正常心律。结论 注重TEE操作护理，手术封堵器械无菌操作配合和术中相关并发症指标观测，可协助经TEE引导下 ASD经皮导管介入封堵术顺利进行，减少手术并发症的发生。

Objective To summarize the perioperative nursing experience of transesophageal echocardiography (TEE) guided percutaneous interventional occlusion of atrial septal defect (ASD). Methods 26 cases of patients with ASD who were treated with TEE-guided percutaneous interventional occlusion from November 2015 to April 2017 were selected. The nursing operation specification was developed from the three aspects of intraoperative TEE operation nursing, aseptic operation coordination of surgical closure device and intraoperative related complications indexes observation, and the specification was strictly enforced during operation, and the nursing effects were summarized and analyzed. Results During TEE operation, 1 patient developed oropharyngeal mucosal edema without damage and bleeding, and there was no teeth loosening among patients. There was no contamination of guide wire during operation. Intraoperative monitoring revealed that 1 patient was with frequent atrial premature beats during the procedure of guide wire transportation, and the patient restored normal heart rhythm after adjusting the direction of guide wire with the surgeon. Conclusion Focusing on TEE operation nursing, aseptic operation coordination of surgical closure device and observation of intraoperative related complications indexes can assist TEE-guided percutaneous interventional occlusion for ASD, and reduce the occurrence of surgical complications.