目的 分析子宫肌壁间妊娠（intramural pregnancy，IMP）的临床表现、治疗方式、临床治疗效果及鉴别诊断，提 高对IMP的认识。方法 回顾与分析本院收治的3例IMP患者的临床资料。结果 3例B超检查均考虑“宫角部妊娠”， 其中2例有体外受精-胚胎移植术史，1例有多次流产史，3例血β-HCG值范围与宫内妊娠很难区别，3例均行腹腔镜 手术，治疗效果良好。结论 IMP的发病率增加可能与日益增多的宫腔操作术如流产术、体外受精-胚胎移植术有 关；临床上IMP极易误诊为宫角妊娠，早期怀疑应尽早腹腔镜手术，治疗效果明确。

Objective Intramural pregnancy (IMP), a very rare type of ectopic pregnancy, was only reported around 100 cases globally in published literature, though an increase of incidence was observed recently. Methods We summarized the clinical data of 3 cases of intramural pregnancy treated in our hospital with respect to aetiology, diagnosis and management. Results Two of the 3 cases underwent in vitro fertilization/embryo implantation. Two had the history of abortion, one of whom had experienced multiple times. All these 3 cases were misdiagnosed of cornual pregnancy by B Ultrasound. Testing of β-HCG failed to provided evidence to distinguish IMP from intrauterine pregnancy. All 3 cases underwent laparoscopic surgery with satisfied outcome. Conclusion The awareness of IMP should be raised due to the increased incidence. The etiology was still unclear, the most acceptable perception could be the consequence of previous uterine surgery, such as a caesarean section or myomectomy, in vitro fertilization/embryo implantation, or repeated abortion. Although it was difficult to differentiate from cornual pregnancy, an earlier laparoscopic surgical intervention would be an appropriate choice for diagnose and appropriate management.