目的 探讨血红蛋白水平与慢性阻塞性肺疾病（chronic obstructive pulmonary disease,COPD）患者严重程度的 相关性。方法 选择2014年10月至2016年10月于我院确诊的300例慢性阻塞性肺疾病患者。根据患者血红蛋白水平 分为低血红蛋白组、正常血红蛋白水平组、高血红蛋白组，比较三组患者的一般资料、BODE评分[气道阻塞程度 (FEV1%)、呼吸困难评分(mMRC评分)、运动能力评分(6MWD)]、不同严重程度（轻-中度/重-极重度）的比例等指 标，并采用Pearson’s 法分析其与血红蛋白水平的相关性。结果 高血红蛋白组和正常血红蛋白组患者的年龄、 冠心病比例、糖尿病比例、mMRC评分及轻-中度/重-极重度的比例显著低于低血红蛋白组（P<0.05），而FEV1%、 FEV1/FVC%及6MWD显著高于低血红蛋白组，差异均有统计学意义（P<0.05），且三组患者随着血红蛋白水平的升高 BODE评分越低，差异均有统计学意义（P<0.05）。相关性分析结果表明血红蛋白水平与BODE指数和FEV1%呈显著负 相关，而与mMRC评分呈正相关。结论 血红蛋白水平与COPD患者的疾病严重程度密切相关，低血红蛋白水平预示着 COPD症状的加重、运动耐量的降低以及生活质量的下降，高血红蛋白对患者疾病程度的影响较小。

Objective To explore the correlation between Hemoglobin levels and severity of chronic obstructive pulmonary disease patients. Methods 300 cases of patients with chronic obstructive pulmonary disease (COPD) diagnosed in our hospital between From October 2014 to October 2016 were chosen. Subjects were categorized as anemic, polycythemic and normocythemic. The BODE score [FEV1%, modified medical research council scale(mMRC score), 6 minutes walking distance(6MWD)] were compared among three group, and the correlation analysis and the proportion of different severity different severity (Light to medium/heavy to extreme serious) were carried with Pearson method. Results The age, the proportions of the coronary heart disease, diabetes, mMRC score in polycythemic or normocythemic the proportion of Light to medium/heavy to extreme serious were significantly lower than those in anemic(P<0.05). But the FEV1%/FEV1/FVC% and 6MWD were significantly higher than those in anemic,(P<0.05). Conclusion Analysis results showed that the hemoglobin level were negative with the BODE index and FEV1 %, but postitive with mMRC score. Conclusion The hemoglobin levels are closely associated with the severity of disease in COPD patients, Anemia in COPD was a risk factor for poorer exercise capacity and quality of life, and these outcomes were linearly associated with hemoglobin. High hemoglobin level had less effects on degree of disease in patients with COPD.