目的 探讨和分析慢性肺源性心脏病(CPHD)患者血N末端B型钠尿肽(NT-pro BNP)和超敏C反应蛋白（Hs-CRP）水平的 临床价值。方法 研究选择2016年10月-2017年8月间在我院治疗的36例CPHD患者当做研究对象，遵循患者的病情分 为甲组、乙组，每组18例。甲组患者是单纯CPHD，乙组患者是CPHD并发慢性阻塞性肺疾病（CODP），评价甲乙两组 患者的NT-pro BNP水平、Hs-CRP水平、PaO2（动脉氧分压）水平、PaCO2（动脉二氧化碳分压）水平。结果 甲组患 者的NT-pro BNP水平、PaCO2水平低于乙组患者，差异对比具有统计学意义。甲组患者的PaO2水平高于乙组患者，差 异对比具有统计学意义。结论 NT-pro BNP水平、Hs-CRP水平对于COPD患者合并CPHD具有重要的鉴别意义，COPD患 者合并CPHD时，NT-pro BNP水平、Hs-CRP水平升高明显，同缺氧存在一定关系。

Objective To investigate and analyze the chronic pulmonary heart disease (CPHD) patients with serum N terminal B type natriuretic peptide (NT-pro BNP) and high sensitive C reactive protein (Hs-CRP) clinical value. Methods The study selected October 2016 -2017 year in August in the 36 CPHD patients in our hospital as the object of study, follow the patients were divided into group A, group B, 18 cases in each group. The group of patients with simple CPHD, group B patients with CPHD complicated with chronic obstructive pulmonary disease (CODP), and evaluation of two groups of patients with NT-pro BNP level, Hs-CRP level, PaO2 (arterial oxygen partial pressure (PaCO2) level. Arterial partial pressure of carbon dioxide). Results The group of patients with NT-pro BNP level, PaCO2 level lower than that of group B patients, the difference was statistically significant. Compared with the group of patients with PaO2 was higher than group B patients, the difference was statistically significant compared. Conclusion NT-pro BNP level, Hs-CRP level for COPD Patients with CPHD have important differential significance. When COPD patients are combined with CPHD, the levels of NT-pro, BNP and Hs-CRP are obviously increased, which is related to hypoxia.