目的 探讨比较磁共振3D-SPACE、3D-True FISP序列在膝关节软骨缺损术前分级中的诊断价值。方法 对经关节镜 证实的膝关节软骨缺损患者43例，于术前一周行3D-SPACE序列和3D-True FISP序列的MRI检查，并与关节镜记录结 果进行对照，比较两序列准确显示膝关节软骨缺损的能力。结果 3D-SPACE比3D-True FISP序列能发现更多数目的 软骨缺损，且在软骨缺损质量显示方面更好，特别是在Ⅰ，Ⅱ级软骨损伤上两者间有统计学差异(P＜0.05)。结论 3D-SPACE较3D-True FISP序列在膝关节软骨缺损分级中具有优势。

Objective To compare the diagnostic value via imaging quality of the articular cartilage of knee with the 3D-SPACE, 3D-True FISP sequences. Methods Before treated by arthroscope in the next week., 43 patients of knee joint were examined with 3D-SPACE and 3D-True FISP sequences at 1.5T MRI .Lesion visualization of articular cartilage were compared. Results 3D-SPACE comparing with 3D-True FISP not only finding more numbers of cartilage injury, but also having significant difference between the cartilage injury at level Ⅰ and level Ⅱ(P<0.05). Conclusions Compared with the 3D-True FISP sequence 3D-SPACE sequence can show the knee cartilage injury better.