摘要
目的 探讨颈内动脉狭窄支架置入血管成形术后发生再灌注损伤的影响因素。方法 选取我院从2014年1月到2016年3 月入院治疗的35例颈内动脉狭窄支架置入血管成形术患者做为研究对象。按照患者颈内动脉狭窄程度分为重度狭窄 组15例与中度狭窄组20例。两组患者均采用颈内动脉狭窄支架置入血管成形术治疗,统计两组患者术后再灌注损伤 几率及影响因素分析。结果 重度狭窄组患者的再灌注损伤率显著高于对照组患者,差异具统计学意义(P<0.05)。 颈内动脉狭窄支架置入血管成形术后再灌注损伤发生率的主要影响因素为患者的年龄、合并疾病及狭窄程度。结论 通过对颈内动脉狭窄支架置入血管成形术后发生再灌注损伤的发生几率及其影响因素统计分析,患者年龄、合并疾 病及狭窄程度等因素对于术后再灌注损伤几率影响较大。
Objective To investigate the internal carotid artery stenosis stenting factors postoperative reperfusion injury in shape. Methods In our hospital from January 2014 to March 2016 35 hospitalized patients with carotid artery stenosis stenting in patients undergoing shaping as a research object. In accordance with internal carotid artery stenosis as severe stenosis group and 15 cases of 20 patients with moderate stenosis. Two groups of patients were treated with internal carotid artery stenosis stent angioplasty, the two groups after statistical probability of reperfusion injury and influencing factors. Results The rate of reperfusion injury in patients with severe stenosis was significantly higher in patients, the difference was statistically significant (P<0.05). Internal carotid artery stenosis stenting angioplasty main factors of postoperative reperfusion injury incidence for age, comorbidities and stenosis patients. Conclusion Based on the internal carotid artery stenosis stent angioplasty reperfusion injury risk of the occurrence of postoperative factors and statistical analysis, patient age, comorbidities and other factors stenosis greater chance of postoperative reperfusion injury affected.
【关键词】颈内动脉狭窄;支架置入血管成形术;再灌注损伤;影响因素
【中图分类号】R543.4
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2016.05.003
前言
有报道指出[1],在我国脑血管病是致残、致死几 率排第一位的慢性病,临床上缺血性脑卒 中发病率 较高,致病因素中颈内动脉狭窄是首位的风险因素, 临床上对于颈内动脉颅外段狭窄的治疗措施,主要以 恢复脑部血流动力学水平,达到治疗脑缺血的目的, 防止患者缺血性卒中的发生。我院从2014年1月开始 研究颈内动脉狭窄支架置入血管成形术后发生再灌注 损伤的影响因素,现报道如下。
罕少疾病杂志
第23卷, 第 6 期
2019年11月
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