摘要
目的 探讨介入治疗对非ST段抬高的急性冠脉综合征(NSTE-ACS)患者心功能的影响。方法 选取2013年2月-2015年 2月期间我院收治的140例非ST段抬高的急性冠脉综合征患者作为观察对象,所有患者采用介入治疗,观察介入术 前及术后非ST段抬高的急性冠脉综合征各项指标和患者心功能的改变情况。结果 介入术后通过对肌酸激酶同工酶 (CK-MB)、心肌钙蛋白(cTn)、左心室舒张末径(LVDD)和左心室射血分数(LEVF)和心功能分级评定结果显示,术后指 标相对于术前有明显改善,增强了心肌灌注能力。同时术后心功能二级以上的患者明显降低。结论 介入治疗可以 改善心室泵血功能,有助于NSTE-ACS患者心功能改善。
Objective To investigate interventional treatment influence on cardiac function in patients with non-ST segment elevation acute coronary syndrome(NSTE-ACS). Methods 140 cases with NSTE-ACS were selected as the object from February 2013 to February 2015 in our hospital, all patients treated with interventional therapy, the NSTE-ACS comprehensive indexes and the change of cardiac function were observe before and after the intervention operation. Results After intervention therapy, postoperative index compared was improved significantly with the ability of cardiac muscle perfusion enhanced based on the creatine kinase (CK-MB), cardiac troponin (cTn), left ventricular enddiastolic diameter (LVDD) and left ventricular ejection fraction (LEVF) and heart function classification results. At the same time, the amount of patient with postoperative heart function more than Grade-2 was decreased significantly. Conclusion Interventional therapy can improve ventricular pump function, which is helpful for the improvement of heart function in patients with NSTE-ACS.
【关键词】介入治疗;非ST段抬高的急性冠脉综合征;心功能;影响
【中图分类号】R541.4
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2016.03.002
前言
NSTE-ACS包括非ST段抬高型心肌梗死和不稳定 心绞痛两类,主要病因是冠状动脉粥样硬化斑块破 裂、继发血栓形成导致急性心肌缺血[1]。临床症状常 常表现为放射性胸骨后痛、胸闷等症状,可导致心律 失常、出血并发症、心力衰竭、乳头肌功能失调、休 克甚至威胁患者生命安全[2]。对于高危NSTE-ACS患者 提倡尽早介入治疗,介入治疗使用心导管技术疏通狭 窄甚至闭塞的冠状动脉管腔,从而改善心肌的血流灌 注,缓解症状[3]。同时配合药物治疗,可明显降低死 亡率、减少并发症、改善患者的预后。
罕少疾病杂志
第23卷, 第 4 期
2019年11月
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