目的 探讨HPV、TCT联合阴道镜在筛查早期宫颈病变中的应用价值。方法 回顾我院从2014年12月到2015年10月门诊 收治的116例宫颈病变患者的临床资料。上述患者入院后即进行HPV、TCT及阴道镜下活检，评估不同检测方法对于 早期宫颈病变的诊断价值。结果 TCT检测阳性(+)患者42例，阳性率为36.21%；HPV检测阳性(+)患者91例，阳性率 为78.45%。经病理检测癌前病变患者共25例。TCT检测与HPV检测癌前病变检出率分别为72%与84%，联合阴道镜检测 后，检出率为100%，差异具统计学意义(P＜0.05)。结论 临床应用HPV、TCT及阴道镜三种技术对于早期宫颈病变的 早期筛查，检测技术各具优势，三种技术联合检测较单一检出率更高，值得临床广泛推广应用。

Objective To investigate clinical value of HPV, TCT combined colposcopy in screening for early cervical lesions. Methods The clinical data of 116 cases with cervical lesions from December 2014 to October 2015 was analyzed retrospectively. HPV, TCT and biopsy under colposcope were underwent after hospital admission in order to evaluate the diagnostic value of different methods for the early detection of cervical lesions. Results TCT test positive (+) 42 patients, the positive rate was 36.21%; HPV test positive (+) of 91 patients, the positive rate was 78.45%. Pathologically detecting precancerous lesions of 25 cases. TCT and HPV testing to detect precancerous lesion detection rates were 72% and 84%, after the united colposcopy, a detection rate of 100%, the difference was statistically significant (p <0.05). Conclusion The clinical application of HPV, TCT and colposcopy for early screening and early detection of cervical lesions have their own advantages, the three combined detection of more than a single detection rate, which was worthy for wider application.