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·综合疾病·

ICU内高钠血症患者采用连续血液净化治疗疗效观察

作者:廖铁达

所属单位:广东省从化区中医医院 (广东 从化 510900)

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摘要

目的 观察使用连续血液净化治疗ICU内高钠血症患者的临床疗效。方法 选取2010年3月-2015年10月ICU收治的高钠 血症患者28例,随机分为观察组与对照组,对照组实施常规保守治疗,观察组采用连续血液净化治疗,对比两组临 床效果。结果 观察组高钠血症症状消失时间、ICU治疗时间及住院时间均明显少于对照组,治疗后两组血钠水平与 APACHEⅡ评分均明显降低,且观察组降低程度更为显著,P<0.05,差异均有统计学意义。结论 对ICU内高钠血症 患者使用连续血液净化治疗,对降低血钠水平有明显的促进作用,能够有效缩短治疗时间,进一步改善患者临床症 状,具有理想的临床效果与推广价值。

Objective To investigate the clinical efficacy of continuous blood purification in the ICU high sodium hyperlipidemia patients. Methods 28 patients in ICU from March 2010 to October 2015 were randomly divided into observation group of continuous blood purification treatment and the control group of routine conservative treatment, and clinical results of two groups were compared. Results The observation group symptoms of hypernatremia time, ICU treatment time and hospital stay were significantly less than those of control group, two groups after treatment with sodium levels APACHEⅡ scores were significantly reduced, while the observation group reducing was much more significant, P < 0.05, differences were statistically significant. Conclusion The patients with hypernatronemia in ICU treated with continuous blood purification can significantly facilitate the reduction of serum sodium level and effectively shorten the treatment time, further improve the clinical sympotoms of patients, having an ideal clinical effect and promotional value.

【关键词】高钠血症;连续血液净化;临床疗效;血钠

【中图分类号】R559

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2016.03.019

前言

在重症监护病房(ICU)内进行救治的患者通常病 情较为危重,病程发展较快且复杂多变,高钠血症是 ICU较为常见且危险的严重并发症,一旦血钠水平异 常升高后,机体水钠代谢功能会随之紊乱。ICU内高 钠血症患者具有较高的死亡率,如救治措施不及时甚 至可以高达近70%[1]。而以往临床上主要针对患者病 情予以对症、支持治疗,缺乏疗效明确、迅速生效的 有效治疗措施。连续血液净化治疗是新型清除机体水 分、溶质恢复水电解质平衡的治疗方式,本文作者对 我院ICU内部分高钠血症患者采用该方式治疗,对比 观察其临床效果以作评估,现报道如下。