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·软组织疾病·

老年患者腰麻联合静脉应用右美托咪定的麻醉效应与安全性

作者:冯智泉

所属单位:广东省肇庆市广宁县人民医院 (广东 肇庆 526300)

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摘要

目的 探析老年患者腰麻联合静脉应用右美托咪定(DMT)麻醉效应以及安全性。方法 择取本院于2014年8月-2016年1 月期间收治的经尿道前列腺电切除术患者114例,按照患者的入院顺序,划分为对照组与研究组,每组各57例。对 照组患者接受常规麻醉,研究组患者接受腰麻联合DMT静脉注射麻醉,对比两组患者的麻醉效应。结果 研究组患者 的最高感觉阻滞平面消退时间、术中镇静评分、低氧饱和发生率、心动过缓发生率、低血压发生率均优于对照组患 者,数据组间差异具有统计学意义(P<0.05)。结论 对老年患者行腰麻+DMT静脉注射麻醉,不仅具有良好的镇痛效 果以及镇静效果,而且临床应用安全性较高,值得临床大面积推广。

Objective To analysze effects and safety of spinal anesthesia and intravenous application given dexmedetomidine (DMT) narcotic in elderly patients. Methods A total of 114 cases received transurethral resection from August 2014 - January 2016 were divided into control group and study group of 57 cases in each group according to the order of admission, The control group patients received underwent conventional anesthesia and the study group patients received spinal anesthesia + DMT intravenous anesthesia, narcosis were compared between among them. Results The study group of patients with the highest sensory block regression time, intraoperative sedation scores, low oxygen saturation rate, the incidence of bradycardia, hypotension rate were better than those of control group with statistically significant (P<0.05). Conclusion Elderly patients underwent spinal anesthesia+DMT intravenous anesthesia, not only has good analgesic and sedative effect, but higher clinical safety and is worth a wide application.

【关键词】老年患者;腰麻;右美托咪定;麻醉效应;安全性

【中图分类号】R323.3

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2016.03.016

前言

右美托咪定(DMT)作为一种激动剂,可以显著刺 激 2肾上腺能受体,中枢抗交感性能良好,镇静效果 与自然睡眠相近,除此之外,还具有较好的镇痛效应 以及稳定患者血流动力学[1]。与腰麻联合使用,可以 延长麻醉时间,减轻患者麻醉恢复早期、手术应激时 的血流动力学应答反应速度,属于围术期高选择性麻 醉合并用药[2]。