目的 提高对罕少疾病组织细胞坏死性淋巴结炎的认知，探讨相关护理措施。方法 结合文献复习，对5例组织细胞 坏死性淋巴结炎的护理进行分析。结果 此病主要表现为颈部淋巴结肿大，伴发热、关节酸痛等，经糖皮质激素治 疗后，其中4例局部肿块消退，切口愈合好。其中1例原切口裂开，予清洁干净，拉拢粘贴并口服消炎药物7d后愈 合，再访1个月创口愈合。结论 糖皮质激素治疗组织细胞坏死性淋巴结炎有显著效果，相应护理措施在一定程度上 促进局部淋巴结消退和减轻药物不良反应。

Objective Aimed to increase the realization of histiocytic necrotizing lymphadenitis (HNL) and study the nursing of this disease. Methods A total of 5 cases of HNL patients were analyzed retrospectively based on the reported study. Results The main characteristics of this disease were cervical lymphadenectasis, fever, joint pain, and so on. The cervical mass were extincted and the incision were healed well after corticosteroid therapy in 4 cases. 1 case of HNL with wound disruption was healed after cleaned the incision, co-opted pasted and oral anti-inflammatory drugs 7 days. One month later the incision healed well. Conclusion HNL is responsive to the corticosteroid therapy. The effective nursing measures will promote the local lymph node regression and reduce adverse drug reactions.