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·胸部疾病·

阿奇霉素序贯疗法治疗小儿支原体肺炎的临床疗效及安全性分 析

作者:曾远辉

所属单位:中山大学附属佛山医院(佛山市第一人民医院)儿科 (广东 佛山 528000)

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摘要

目的 探究阿奇霉素序贯疗法治疗小儿支原体肺炎的疗效与安全性,为今后的临床工作提供参考依据。方法 将我院 2012年4月-2014年4月收治的100例小儿支原体肺炎患者纳入本次研究,按照治疗方式的不同分为对照组与实验组, 对照组给予红霉素治疗,实验组给予阿奇霉素序贯疗法治疗,观察两组患儿治疗后的效果、临床症状改善时间及不 良反应。结果 实验组治疗总有效率、症状改善时间均优于对照组,而不良反应明显少于对照组(P<0.05),差异 具有统计学意义。结论 阿奇霉素序贯疗法治疗小儿支原体肺炎效果确切,能迅速缓解患儿的临床症状,同时无严 重不良反应,是一种价值较高的治疗药物,可在临床进行借鉴推广。

Objective To explore the azithromycin sequential therapy for children with mycoplasma pneumonia curative effect and security, provide a reference basis for the future clinical work. Methods From April 2012 - April 2014 treated 100 cases of children with mycoplasma pneumonia patients in this study, according to the different methods of treatment were divided into control group and observation group, control group given erythromycin treatment, the observation group was given azithromycin sequential therapy, observe the effect of the two groups after treatment in children with, clinical symptoms improved time and adverse reactions. Results Observation group were better than control group total effective rate, symptoms improve time, adverse reactions and significantly less than the control group (P<0.05), the difference is statistically significant. Conclusion azithromycin sequential therapy for children with mycoplasma pneumonia effect is exact, can quickly relieve the patient's clinical symptoms, no serious adverse reactions at the same time, higher treatment is a kind of value, can be used in clinical promotion.

【关键词】阿奇霉素;小儿支原体肺炎;效果;安全性

【中图分类号】R978.15;R563.1

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2015.03.009

前言

小儿支原体肺炎为儿科常见病,是肺炎支原体引 起的呼吸道感染,常表现为刺激性咳嗽、发热等症状 [1]。阿奇霉素是大环内酯类抗生素,抗菌作用强,菌 谱广泛,对呼吸系统、生殖系统、泌尿系统与皮肤软 组织感染等具有明显的抗菌作用。我院采用阿奇霉素 对50例小儿支原体肺炎患者进行了治疗,发现其临床 效果良好,且安全性高,现将结果报告如下。