论著-头颈部
骨巨细胞瘤伴动脉瘤样骨囊肿的CT、MRI影像表现及文献复习附一例报告
作者:刘美兰 杜兆峰
所属单位:北京中医药大学第四附属医院枣庄 市中医院影像科 (山东 枣庄 277100)
PDF摘要
目的探讨骨巨细胞瘤伴动脉瘤 样骨囊肿的CT、MRI影像学表现及影像诊 断要点。方法 以2016年1月-2016年3月我 院收治的1例经手术病理证实的骨巨细胞 瘤伴动脉瘤样骨囊肿患者为研究对象,1 例患者均施行CT及MRI扫描检查。结果 1 例患者经CT扫描可见不同程度膨胀性改 变,骨皮质变薄(或骨壳不完整),CT典型 特征为骨囊肿与原发灶的边界不够清晰, 密度欠均匀,包含原发灶区域(实性)及 继发较薄;MRI影像学表现为T1WI和T2WI 扫描提示病灶边缘存在低信号(呈不完整 性),骨囊肿主体T1WI扫描提示存在低或 中高信号,T2WI扫描有不均匀的高信号; MRI增强扫描提示病灶囊壁及灶内呈分隔 强化,囊性处并未见明显强化;病灶主体 (原发骨巨细胞瘤)经T1WI扫描提示有中和 低信号,T2WI扫描提示明显低、中、高混 杂信号。结论 骨巨细胞瘤伴动脉瘤样骨 囊肿患者CT、MRI影像学表现都具有特征 性,而其中MRI在鉴别原发灶及继发病灶 方面较CT更具优势,同时结合患者临床表 现可明显提高本病确诊率。
Objective To investigate the imaging features of CT and MRI in diagnosis of giant cell tumor of bone with aneurysmal bone cyst. Methods A case of giant cell tumor of bone with aneurysmal bone cyst confirmed by surgery and pathology in our hospital from January to March 2016 was enrolled in the study. The patient was examined with CT and MRI. Results CT scan showed different degrees of expansive changes and cortical thinning (or incomplete bony shell) in the patient. The typical features of CT were that the boundary between the bone cyst and primary lesion was not clear enough and the density was not uniform, including the primary lesion area (solid) and thin secondary lesion area. MRI imaging findings showed there was a low signal at the edge of lesion (incompleteness) in T1WI and T2WI scan , and the T1WI scan of main body of bone cyst indicated that there was a low or medium-high signal, and the T2WI scan showed a non-uniform high signal. The MRI enhanced scan showed that separate enhancement in lesion capsule wall and in lesions, and no obvious enhancement at the cystic site. The main body of lesion (primary giant cell tumor) showed medium and low signals in T1WI scan, and obviously low, medium and high mixed signals in T2WI. Conclusion CT and MRI images of giant cell tumor of bone with aneurysmal bone cyst are characteristic. MRI is superior to CT in the differential diagnosis of primary and secondary lesions. The combination with clinical manifestations of patients can significantly improve the diagnosis rate of the disease.
【关键词】骨巨细胞瘤;动脉瘤样骨囊肿;CT;MRI;诊断效能
【中图分类号】R714.257
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.10.044
前言
骨巨细胞瘤为骨科较少见的骨肿瘤,常表现为局部间隙性疼痛、 局部包块、邻近关节活动受限等,发病率占骨髓瘤总发病率8%左右; 本病有明显侵袭性、易复发和局部转移等特征,因而治疗后预后效果 不佳[1]。骨巨细胞瘤的良性病变常见类型为动脉瘤样骨囊肿,严重威 胁患者生命安全,临床对本病治疗尚缺乏有效方案,因此尽早准确诊 断是降低患者病死率及改善预后的关键[2]。目前对骨巨细胞瘤伴动脉 瘤样骨囊肿诊断主要依据影像学手段,CT及MRI是临床中常用影像学 诊断技术,早期文献报告指出CT及MRI诊断骨巨细胞瘤有一定临床价 值[3-4],但有关两者诊断效能差异尚无定论,为此选取我院收治的1例 骨巨细胞瘤伴动脉瘤样骨囊肿进行对照性分析,结果简述如下。
中国CT和MRI杂志
第16卷, 第 10 期
2018年10月
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