简体中文

论著-头颈部

MRI多序列扫描在脑胶质瘤术前术后中的应用

作者:刘安龙

所属单位:河南省安阳市人民医院放射科(河南 安阳 455000)

PDF

摘要

目的 分析MRI多序列扫描在 脑胶质瘤术前术后中的应用价值。方 法 收集2013年3月-2016年3月我院经手 术病理证实为脑胶质瘤的48例患者的临 床资料,所有患者手术前后均接受MRI 多序列扫描,分析MRI在脑胶质瘤术前 诊断及术后评估中的价值。结果 脑胶 质瘤患者MRI检出单发39例(81.25%), 多发9例(18.75%);肿瘤位于额叶13例 (27.08%),颞叶8例(16.67%),顶叶10 例(20.83%),枕叶8例(16.67%),颞顶 叶交界区4例(8.33%),额顶叶交界区5 例(10.42%);T1WI序列呈低信号或等信 号36例(75.00%),T2WI序列呈稍高或高 信号48例(100.00%),T1 FLAIR呈等信 号或低信号30例(62.50%),呈混杂信号 18例(37.50%),T2 FLAIR呈高信号34 例(70.83%);MRI见伴囊变、坏死19例 (39.58%),伴出血3例(6.25%),见钙化1 例(2.08%);增强扫描呈明显环状强化35 例(72.92%),结节状强化3例(6.25%), 呈轻度强化7例(14.58%),未见明显强化 3例(6.25%);见占位效应及水肿带44例 (91.67%),4例(8.33%)未见占位效应及 水肿带;术后恢复良好者MRI见片状软化 灶,伴肿瘤残留或播散者原发灶见明显 强化,边界不清。结论 MRI多序列扫描 可为明确脑胶质瘤部位、大小、形态、 特点及强化特征,鉴别肿瘤性质,为手 术方式制定提供参考,而术后进行MRI检 查则可明确患者术后肿瘤残留及复发情 况,为患者预后改善提供依据。

Objective To analyze the application value of MRI multi-sequence scan before and after the operation for glioma. Methods The clinical data of 48 patients with glioma confirmed by operation and pathology in our hospital from March 2013 to March 2016 were collected. All patients underwent MRI multiple-sequence scan before and after operation, and the value of MRI in preoperative diagnosis and postoperative evaluation of glioma. Results MRI detected in single glioma in 39 cases (81.25%) and multiple gliomas in 9 cases (18.75%). The tumors were located in frontal lobe in 13 cases (27.08%), temporal lobe in 8 cases (16.67%), parietal lobe in 10 cases (20.83%), occipital lobe in 8 cases (16.67%), temporal parietal junction area in 4 cases (8.33%) and frontal parietal junction zone in 5 cases (10.42%). T1WI sequence showed low signal or equal signal in 36 cases (75%), T2WI sequence showed slightly high or high signal in 48 cases (100.00%), T1 FLAIR showed equal signal or low signal in 30 cases (62.50%) and mixed signal in 18 cases (37.50%), while T2 FLAIR showed high signal in 34 cases (70.83%). MRI showed cystic degeneration and necrosis in 19 cases (39.58%), hemorrhage in 3 cases (6.25%), calcification in 1 case (2.08%). Enhanced scan showed obvious ring enhancement in 35 cases (72.92%), nodular enhancement in 3 cases (6.25%), mild enhancement in 7 cases (14.58%) and no obvious enhancement in 3 cases (6.25%). There were 44 cases (91.67%) with occupying effects and edema zone, and 4 cases (8.33%) without occupying effect or edema zone. MRI showed patchy softening lesions in patients who recovered well after operation, with tumor residual or obvious enhancement of primary lesions in disseminated patients, and the boundary was not clear. Conclusion MRI multi-sequence scan can clearly show the location, size, shape, characteristics and enhanced features of gliomas and identify the nature of tumors, and providing references for making operation plan. Postoperative MRI examination can clearly show residual tumor and recurrence after operation, providing the basis for improving the prognosis of patients.

【关键词】脑胶质瘤;磁共振成像;手术;诊断

【中图分类号】R65;R74

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.10.008

前言

脑胶质瘤是起源于神经胶质细胞的中枢神经系统肿瘤类型,包 括星形细胞瘤、脉络丛肿瘤、少突-星形胶质细胞瘤、少突胶质细胞 瘤等,其中星形细胞瘤多见[1]。且大部分脑胶质瘤早期缺乏特异性症 状,部分伴头晕、头痛等非特异性征象,易被忽视,而当患者出现突 发性癫痫症状时病情已进展至中晚期,临床治疗难度大[2]。早期检出 脑胶质瘤并予以积极的干预则是改善患者预后的关键。目前对脑胶质 瘤多采用以手术切除为主的综合疗法,但部分疗效有限,患者术后复 发率高[3]。肿瘤侵袭性生长为引起脑胶质瘤术后复发的主要原因,而 评定患者术后情况,明确术后肿瘤复发、转移情况则可为预后评估及 临床治疗提供参考。早期对脑胶质瘤的术前诊断及术后转移判定仅依 靠临床症状或脑脊液穿刺检查,前者主观性强,后者为侵袭性操作, 患者可接受度低[4]。相对而言,MRI可实现多序列成像,明确肿瘤大 小、位置、形态特点及其周围白质传导束的关系,且有良好的软组织 分辨率,同时安全、无创。为探讨MRI多序列扫描在脑胶质瘤术前、术 后的应用价值,现对医院收治的48例脑胶质瘤患者的临床资料进行了 回顾性分析,报道如下。