摘要
目的探讨光学相干断层扫描 (OCT)在孔源性视网膜脱离(RRD)患者术后 中的应用价值。方法 选取2014年6月至 2017年6月我院收治的RRD患者120例(120 只患眼,120只健康眼)为研究对象,均 行巩膜扣带手术,术后行全面眼科检查测 定最佳矫正视力(BCVA),并在术后3d、2 周、1个月、3个月、6个月随诊时对双眼 进行OCT检查,测量其黄斑中心凹视网膜 厚度、黄斑区视网膜下积液(SMF)高度及 光感受器内外连接(IS/OS)交界线、视网 膜外界膜(ELM)等微结构改变,分析术后 黄斑区微结构改变与其视力预后的关系。 结果 术前OCT可见IS/OS与ELM层断裂, 光感受器外节反光带不规则或增粗,术 后IS/OS、ELM形态主要为IS/OS、ELM连 续,IS/OS断裂、ELM连续,IS/OS连续、 ELM断裂,IS/OS、ELM均断裂;术后2周患 眼BCVA有不同程度提高,且术后3个月、 6个月BCVA较术前明显提高(P<0.05); 术前患眼SMF高度、黄斑中心凹视网膜厚 度高于对侧健康眼(P<0.01),术后3d、 2周、1个月、3个月患眼黄斑中心凹视网 膜厚度低于术前,但仍高于对侧健康眼(P <0.01),术后6个月差异无统计学意义(P >0.05);术前SMF高度、黄斑中心凹视网 膜厚度与术后6个月患眼BCVA呈负相关(P <0.05)。结论 OCT在RRD术后有较高应用 价值,可较好评价其黄斑中心凹视网膜厚 度、SMF、IS/OS、ELM等微结构,值得在 临床推广实践。
Objective To explore the application values of optical coherence tomography (OCT) in postoperation of patients with rhegmatogenous retinal detachment (RRD). Methods A total of 120 cases of RRD patients (120 affected eyes, 120 healthy eyes) admitted to our hospital from June 2014 to June 2017 were enrolled in this study and were given the scleral buckling surgery. The best corrected visual acuity (BCVA) was determined by comprehensive ophthalmoscopy after operation, and the OCT was performed on both eyes at the follow-up of 3d, 2 weeks, 1 month, 3 months and 6 months after operation. The macular foveal retinal thickness, subretinal macular fluid (SMF) height and the photoreceptor inner segment/outer segment (IS/OS) borderline and the external limiting membrane (ELM) and other microstructures were measured. And the relationship between macular microstructure changes and visual acuity prognosis after operation was analyzed. Results The preoperative OCT showed that the IS/OS and ELM layers were ruptured, and the photoreceptor outer reflection band was irregular or thickening. The postoperative IS/OS and ELM morphology were mainly continuous IS/ OS and ELM, ruptured IS/OS and continuous ELM, continuous IS/OS and ruptured ELM, and ruptured IS/OS and ELM. The BCVA of affected eyes was increased with different degree at 2w after operation, and the BCVA at 3 months and 6 months after operation was significantly higher than that before operation (P<0.05). The preoperative SMF height and the macular foveal retinal thickness of the affected eyes were higher than those of the contralateral healthy eyes (P<0.01), and the macular foveal retinal thickness at 3d, 2 weeks, 1 month and 3 months after operation was lower than that before operation but was still higher than that of contralateral healthy eyes (P<0.01), but there was no significant difference at 6 months after operation (P>0.05). Preoperative SMF height, macular foveal retinal thickness were negatively correlated with the BCVA of affected eyes at 6 months after operation (P<0.05). Conclusion OCT in the postoperation of RRD has high application values, which can evaluate its macular foveal retinal thickness, SMF, IS/ OS, ELM and other microstructures, and it is worthy of clinical promotion and practice.
【关键词】OCT;孔源性视网膜脱离;术后
【中图分类号】R772
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.10.005
前言
孔源性视网膜脱离(RRD)为临床常见的严重致盲性疾病,手术是目 前治疗RRD的唯一方法,目前采用的视网膜复位术有巩膜扣带术(SB)、 玻璃体切割术(PPV)等,但视网膜成功复位后,其视功能恢复常不尽 人意,视力不提高或提高后再次下降,尤其是黄斑功能病变等,因此 应加强术后眼底检查、诊断及随访[1-2]。光学相干断层扫描(optical coherence tomography,OCT)可直观、无创地反映黄斑组织形态结构, 检测视网膜下液的存在及吸收等微细病理变化,因此在RRD术后随访中 有一定应用价值[3-4]。本文分析了RRD患者术后行OCT检查结果及最佳视 力矫正情况,结果如下。
中国CT和MRI杂志
第16卷, 第 10 期
2018年10月
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