摘要
目的探讨CT小肠造影(CTE)对 炎症性肠病(IBD)的诊断价值。方法 选 择2015年1月-2017年12月间收治的80例 拟诊为IBD的患者作为研究对象,所有 患者均经CTE检查;以临床表现、肠镜和 病理组织学结果等检查综合判断为金标 准,评估CTE检查IBD影像学表现及诊断 结果,计算灵敏度、特异度、准确率、 阴性预测值和阳性预测值。结果 CTE诊断 IBD53例,非IBD27例,灵敏度83.02%、 特异度77.78%、准确率81.25%、阳性 预测值88.00%、阴性预测值70.00%; CTE诊断克罗恩病灵敏度83.78%、特异 度88.37%、准确率86.25%、阳性预测 值86.11%、阴性预测值86.36%;CTE诊 断溃疡性结肠炎灵敏度81.25%、特异度 98.44%、准确率95.00%、阳性预测值 92.86%、阴性预测值95.45%。结论 CTE 是有效诊断IBD的方法,也有助于鉴别诊 断克罗恩病和溃疡性结肠炎。
Objective To explore the diagnostic value of CT enterography (CTE) in the inflammatory bowel disease (IBD). Methods 80 cases of patients with probable IBD admitted from January 2015 to December 2017 were selected for the study and were examined by CTE. The comprehensive judgments of clinical manifestations, colonoscopy and histopathological findings were taken as gold standards, and the imaging findings and diagnostic results of CTE were evaluated in the diagnosis of IBD, and the sensitivity, specificity, accuracy, negative predictive value and positive predictive value were calculated. Results CTE showed there were 53 cases of IBD and 27 cases of non-IBD, and the sensitivity, specificity, accuracy, positive predictive value and negative predictive value were 83.02%, 77.78%, 81.25%, 88.00% and 70.00% respectively. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of CTE were 83.78%, 88.37%, 86.25%, 86.11% and 86.36% respectively in diagnosis of Crohn's disease, and were 81.25%, 98.44%, 95.00%, 92.86% and 95.45% respectively in diagnosis of ulcerative colitis. Conclusion CTE is an effective method for diagnosing IBD, and it also helps in the differential diagnosis of Crohn's disease and ulcerative colitis.
【关键词】炎症性肠病;CT小肠造影; 诊断
【中图分类号】R574.5;R445.3
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.10.041
前言
炎症性肠病(IBD)是一类病因不明且主要累及肠道的特发性炎症性 疾病,包括溃疡性结肠炎(UC)和克罗恩病(CD)两种类型,两者临床及 内镜下表现均可相似,易在诊治中混淆[1]。相关流行病学研究显示, 近年来我国IBD发病率明显增多,呈逐年上升趋势[2]。目前临床已有较 多IBD诊断方法,但胃肠镜、消化道钡餐诊断IBD均有一定缺陷,而近 年来有研究显示CTE在诊断小肠疾病方面优势独特,认为CTE不仅能检 出常规横断面较难发现的病变、定位简捷准确,还可从多个平面观察 小肠[3]。基于此,本研究选取80例拟诊为IBD的患者作为研究对象,以 探究CTE对IBD的诊断价值,现报告如下。
中国CT和MRI杂志
第16卷, 第 10 期
2018年10月
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