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MRI多参数扫描在诊断前列腺癌中的应用价值

作者:姚鑫林 黄 武

所属单位:四川省成都市天府新区人民医院放射科(四川 成都 610213)

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摘要

目的探究MRI多参数扫描在诊 断前列腺癌中的应用价值。方法 回顾性 分析于我院就诊且疑似前列腺癌的62例 患者临床资料,全部患者均行MRI检查, 将MRI检查结果与病理穿刺活检结果进行 对比,分析MRI在诊断前列腺癌中的灵敏 度、特异度及准确度,并分析前列腺癌 患者的MRI图像特征。结果 MRI在诊断前 列腺癌中的灵敏度为90.48%,特异度为 85.00%,准确率为88.71%。前列腺癌患 者的T2WI多呈斑片状低信号,在行弥散 加权成像(DWI)扫描图像中病灶部位存 在异常高信号,表面扩散系数降低。结论 MRI多参数扫描在诊断前列腺癌中具有重 要的应用价值,其灵敏度、特异度及准 确度都较高,可以帮助临床诊断前列腺 癌,值得临床推广。

Objective To explore the application value of MRI multi-parameter scanning in the diagnosis of prostate cancer. Methods The clinical data of 62 patients with suspected prostate cancer treated in our hospital were analyzed retrospectively. All patients were diagnosed with MRI. The MRI examination results were compared with the pathological biopsy results. The sensitivity, specificity and accuracy of MRI in the diagnosis of prostate cancer were analyzed, and the features of MRI images of prostate cancer patients were analyzed. Results The sensitivity, specificity and accuracy of MRI were 90.48%, 85.00% and 88.71% in the diagnosis of prostate cancer. In patients with prostate cancer, T2WI was mostly patchy and abnormal low signals in the periphery of the lesion. In the images of diffusion-weighted imaging (DWI) scan, there was an abnormally high signal at lesion site and the reduced surface diffusion coefficient. Conclusion MRI multi-parameter scanning had important application value in the diagnosis of prostate cancer, and it has high sensitivity, specificity and accuracy, and it can help clinical diagnosis of prostate cancer, therefore it is worthy of clinical promotion.

【关键词】MRI;多参数成像技术;前列腺癌;诊断

【中图分类号】R737.25

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.10.036

前言

前列腺癌(prostate cancer,PCa)是常见男性生殖系统恶心肿 瘤,研究显示,近年来PCa发病率及死亡率都呈上升趋势,PCa分别占 全部癌症发病率和死亡率的第6为和第9位,严重危害了我国男性身体 健康和生活质量[1]。因此,对PCa进行早发现、早诊断及早治疗,有利 于控制疾病的发展和预后[2-3]。目前,临床上检查PCa的影像学方法主 要有超声、CT和MRI,但超声和CT对软组织的分辨能力较低,检查缺乏 特异性,从而大大限制了它们在PCa中的检查,MRI对软组织的分辨能 力较高,故MRI为PCa主要的影像学检查方法[4]。近年来,随着MRI技术 不断的发展,MRI对PCa的检出率不断提高,多参数MRI(mp-MRI)具有无 创性、多参数、多序列成像特点,被认为是PCa最佳的影像学检查方 法[5]。因此,本研究回顾性分析我院62例前列腺癌患者的临床资料, 旨在进一步探索MRI多参数扫描在诊断前列腺癌中的应用价值。