摘要
目的分析特发性肉芽肿性乳腺 炎(IGM)的磁共振特征,提高对本病的 认识及术前诊断正确率。方法 收集2014 年1月至2017年12月期间我院行乳腺磁共 振检查并经病理证实为特发性肉芽肿性 乳腺炎的16例患者资料,依据美国放射 学会提出的乳腺影像报告和数据系统磁 共振成像(BI-RADS-MRI)标准,回顾性分 析病变的磁共振表现,包括形态学、平 扫T1WI及T2WI信号、动态增强(DCE)、 时间-信号强度曲线(TIC)类型及表观 扩散系数(ADC)值。结果 共16例患者 均为单侧病灶,右侧11例,左侧5例,磁 共振平扫T1WI均呈等或稍低信号,T2WI 均呈不均匀高信号,增强扫描呈肿块状 强化9例,非肿块状强化6例。可见异常 强化的15例患者中,病灶均边界不清, 内均可见囊变信号,增强扫描14例早期 (注射2min内)见快速强化,TIC呈流 入型1例、平台型10例、流出型3例。13 例累及乳头、乳晕及临近皮肤,5例与 胸大肌间脂肪间隙消失。13例周围见增 粗迂曲血管。6例伴同侧腋窝淋巴结肿 大。16例患者中可测得ADC值者14例,范 围0.87×10-3mm/s-1.97×10-3mm/s。结论 DCE、TIC类型结合形态学分析、临床病 史综合考虑有助于提高特发性肉芽肿性 乳腺炎术前诊断的正确率。
Objective To analyze the MRI features of idiopathic granulomatous mastitis(IGM) and to improve the preoperative diagnostic accurancy of IGM. Methods A total of 16 patients with pathologically-proved IGM, who were encountered at Fujian Province Cancer Hospital during the period from Jan 2014 to Dec 2017, were enrolled in this study. Breast MRI examination was performed in all patients.According to Breast Imaging and Reporting Data System Magnetic Resonance Imaging(BI-RADS-MRI) standard, which was proposed by American Radiological Society, the MRI manifestations, including morphology, signal intensity on plain T1WI and T2WI, dynamic contrast enhanced MRI(DCE-MRI), the pattern of time-signal intensity curve(TIC) and apparent diffusion coefficient (ADC) values, were retrospectively analyzed. Results The lesions of 16 cases located in unilateral breast, 11 cases on the right breast and 5 cases on the left. All of them presented iso-intensity and hypo-intensity signal on T1WI, and presented heterogeneous hyper-intensity signal on fat suppressed T2WI. On contrast enhanced MRI, the enhanced lesions showed mass-like enhancement in 9 cases and non-mass like enhancement in 6 cases, all of the enhanced lesions appeared as unclear edge and cystic areas. 14 lesions presented with fast enhancement in 2 minutes, and the TIC types presented as inflow type, insistent type, and outflow type in 1, 10 and 3 lesions respectively. 13 cases showed nipple involved and skin thickening. 5 cases showed fuzzy fat gap between lesion and pectoralis major. There were 13 cases with supplying arteries dilated. 6 cases with ipsilateral axillary lymph nodes enlarged. ADC values ranged from 0. 87×10-3mm/s to 1.97×10-3mm/s in 14 cases. Conclusion The DCE-MRI and TIC curve combined with morphology and clinic data, can help to improve the preoperative diagnostic accurancy of IGM.
【关键词】特发性肉芽肿性乳腺炎;磁共振成像;时间-信号强度曲线
【中图分类号】R655.8;R814.41
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.10.028
前言
乳腺炎是女性最常见的乳腺疾病之一,特发性肉芽肿性乳腺炎 (idiopathic granulomatous mastitis,IGM),又称乳腺肉芽肿或肉 芽肿性小叶炎,临床较少见,是指局限于乳腺小叶内的非干酪样、 坏死性肉芽肿性炎,常以乳腺无痛或疼痛性肿块就诊,常被误诊为 乳腺癌。本文回顾性分析16例经病理证实为特发性肉芽肿性乳腺炎 的患者的乳腺磁共振表现,包括形态学、平扫T1WI、T2WI、动态增 强(dynamic contrast enhanced,DCE)、时间-信号强度曲线(timesignal intensity curves,TIC)类型及表观扩散系数(apparent diffusion coefficient,ADC)值,旨在提高对本病的认识,减少临床 误诊,避免不必要的手术。
中国CT和MRI杂志
第16卷, 第 10 期
2018年10月
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