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低剂量CT扫描在诊断早期肺癌中的应用

作者:单世民 毛毅敏 孙瑜霞

所属单位:河南科技大学第一附属医院呼吸科(河南 洛阳 471000)

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摘要

目的探讨低剂量电子计算机断 层扫描(CT)在诊断早期肺癌中的应用。 方法 选取2016年2月-2017年6月在我院 健康体检中心检查发现肺癌后经肿瘤内 科确诊为早期肺癌患者共100例,将采 用常规剂量CT扫描的48例患者纳入对照 组,采用低剂量CT扫描的52例患者纳入 观察组,比较两组患者图像质量和结节 检出情况。结果 观察组和对照组图像 质量比较,无统计学意义(P>0.05)。 对照组剂量长度(DLP)、有效放射剂量 (ED)分值高于观察组,有统计学意义(P <0.05)。观察组结节平均直径和检出结 节数目高于对照组,差异有统计学意义 (P<0.05)。结论 低剂量CT在能够保证 图像质量的情况下,不影响早期肺癌的 检出率,并减小受检者的辐射损伤。

Objective To explore the application of low dose computed tomography (CT) in the diagnosis of early lung cancer. Methods During the period from February 2016 to June 2017, 100 cases of lung cancer were found in the medical examination center of our hospital and suspected of lung cancer, and then diagnosed as early lung cancer by the oncology department. A total of 48 cases healthy examiner treated with routine dose CT scan were enrolled in the control group, and 52 cases treated with low dose CT scan were included in the observation group. The image quality and nodule detection were compared between the two groups. Results There was no significant difference in image quality between the two group (P>0.05). The dose-length product (DLP) and effective radiation dose (ED) in the control group were higher than those in the observation group (P<0.05). The average diameter of nodules and the number of detected nodules in the observation group were significantly higher than those in the control group (P<0.05). Conclusion Low dose CT can ensure the image quality without affecting the detection rate of early lung cancer and reducing the radiation damage of the subjects.

【关键词】低剂量;常规剂量;CT; 早期肺癌;应用

【中图分类号】R734.2;R814.42

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.10.024

前言

肺癌的发病率和死亡率高居恶性肿瘤之首,与患者发现肺癌时肺 癌所处的进展时期有很大关系[1]。仅有小部分患者在患病早期被诊断 为肺癌,大部分患者则因出现肺癌相关临床症状而就诊,此时已为中 晚期肺癌[2]。肺癌的早期诊断有利于肿瘤的及时控制,延长患者生存 时长。由于早期肺癌患者,尤其是周围肺野的小癌肿,患者常无特征 性临床表现,影像学检查在肺癌的早期诊断、指导治疗和病情观察中 显得至关重要[3]。本研究通过运用两种不同剂量的电子计算机断层扫 描(Computed Tomography,CT)扫描,监测早期肺癌的控制效果和治疗 进展,取得良好效果,现将结果报道如下。