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三维超声与MRI在评估冠心病合并室壁瘤患者左心室功能中的临床比较

作者:杨汇娟1 王 艳2

所属单位:1.新乡医学院第三附属医院超声医学科(河南 新乡 453000) 2.郑州大学第二附属医院超声科(河南 郑州 450014)

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摘要

目的探讨三维超声与核磁共振 成像(MRI)在评估冠心病(CHD)合并室壁 瘤患者左心室功能中的临床价值,并进行 比较。方法 回顾性分析新乡医学院第三 附属医院及郑州大学第二附属医院行外科 手术治疗的40例CHD合并室壁瘤患者的临 床资料,比较室壁瘤运动状态、大小、 左心室功能三维超声和MRI检查结果。结 果 三维超声诊断室壁运动状态的符合率 为39.67%;二维超声、三维超声、MRI术 前左室射血分数(LVEF)、左心室舒张末容 积(LVEDV)、左心室收缩末容积(LVESV)所 测值均存在显著差异(P<0.05);术后,三 维超声与MRI、二维超声所测值无显著性 差异(P>0.05),二维超声LVEDV、LVESV 所测值较MRI所测值偏小(P<0.05);三维 超声术前LVEF、LVEDV、LVESV所测值与 MRI所测值间具有良好的相关性,r值分 别为0.65、0.71、0.74(P<0.05);三维 超声术后LVEF、LVEDV、LVESV所测值与 MRI所测值间具有良好的相关性,r值分别 为0.73、0.75、0.76(P<0.05)。结论 三 维超声在测定CHD合并室壁瘤患者左心室 容积、功能方面更接近MRI所测值,但在 判断室壁运动状态方面准确性较差,MRI 可准确判断CHD合并室壁瘤患者左心室功 能。

Objective To explore and compare the clinical values of three-dimensional ultrasound and magnetic resonance imaging (MRI) in evaluating the left ventricular function of patients with coronary heart disease (CHD) complicated with ventricular aneurysm. Methods The clinical data of 40 cases of patients with CHD complicated with ventricular aneurysm treated with surgery in the Third Affiliated Hospital of Xinxiang Medical College and the Second Affiliated Hospital of Zhengzhou University were analyzed retrospectively. The ventricular aneurysm motion, ventricular aneurysm size and the the left ventricular function examination results by three-dimensional ultrasound and MRI were compared. Results Preoperative MRI examination showed that there were 59 paradoxical motion segments and 62 non-motion ventricular wall segments among 40 patients, of which 13 segments were recoverable by preoperative determination and were in accordance with intraoperative diagnosis. And postoperative MRI showed there were wall thickening changes in the 13 segments. Three-dimensional ultrasound results showed that there were 29 paradoxical motion segments and 28 non-motion wall segments, of which 6 were recoverable. The coincidence rate of three-dimensional ultrasound was 39.67% in the diagnosis of wall motion. There were significant differences in the preoperative measured values of the left ventricular ejection fraction (LVEF), left ventricular end diastolic volume (LVEDV) and left ventricular end systolic volume (LVESV) by two-dimensional ultrasound, three-dimensional ultrasound and MRI (P<0.05), and there was no significant difference in the postoperative measured values by two-dimensional ultrasound, three-dimensional ultrasound and MRI (P>0.05), and the measured values of LVEDV and LVESV by two-dimensional ultrasound were lower than those by MRI (P<0.05). The preoperative measured values of LVEF, LVEDV and LVESV by three-dimensional ultrasound had a good correlation with the measured values by MRI , and the rvalues were 0.65, 0.71, 0.74 (P<0.05). The postoperative measured values of LVEF, LVEDV and LVESV had a good correlation with the measured values by MRI, rvalues were 0.73 ,0.75, 0.76 respectively (P<0.05). Conclusion The measured values of left ventricular volume, function by three-dimensional ultrasound were close to the measured values by MRI among patients with CHD complicated with ventricular aneurysm, but the former one is poor in determining the accuracy of ventricular wall motion state, and MRI can accurately determine the left ventricular function of patients with CHD complicated with ventricular aneurysm.

【关键词】三维超声;MRI;冠心病;室壁瘤;左心室功能

【中图分类号】R541

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.10.019

前言

室壁瘤是由冠心病(coronary heart disease,CHD)患者在大面 积心肌梗死后梗死区域坏死的心肌逐渐形成纤维瘢痕组织,病变区域 室壁变薄、向外膨胀所致,常发生于左心室,在心脏收缩时呈反常运 动或丧失活动能力[1]。反复发作的室性心律失常、充血性心力衰竭为 CHD合并室壁瘤患者典型的临床表现,严重影响患者的心功能,外科 室壁瘤切除术是目前最积极有效的治疗手段[2]。MRI是测定CHD合并室 壁瘤患者左心室容量和功能的“金标准”,但存在诸多限制因素,三维超声心动图能全面显示左心室 形态,使便捷、准确地评估CHD 合并室壁瘤患者的心功能成为可 能[3-4]。本研究回顾性分析新乡医 学院第三附属医院及郑州大学第 二附属医院行外科手术治疗的40 例CHD合并室壁瘤患者的临床资 料,旨在比较三维超声与MRI对其 术前、术后左心室功能评估的价 值,报道如下。