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脉络膜黑色素瘤的核磁诊断价值

作者:燕玉清 赵 红

所属单位:1.天津市海河医院 (天津 300350) 2.天津市眼科医院 (天津 300020)

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摘要

目的分析32例(32只眼)脉络 膜黑色素瘤的核磁共振信号特征与病理 和眶内蔓延的关系。方法 对天津市眼 科医院2003年9月至2014年3月收治的脉 络膜黑色素瘤患者32例(32只眼)进行回 顾性研究。结果 32例脉络膜黑色素瘤 的核磁显像中有29例在T1W1呈高信号、 T2W呈低信号;3例在T1W1呈中等信号、 T2W1呈低信号(2例侵犯睫状体和前部脉 络膜,均为混合型细胞型伴有视网膜下 和玻璃体出血;1例梭形细胞型,伴有渗 出性视网膜脱离),可能因视网膜下和玻 璃体出血,瘤体并发出血伴大量肿瘤细 胞坏死,信号特征不典型;1例在T1WI和 T2WI呈中等信号,可能是由于黑色素含 量少。结论 核磁共振对于脉络膜黑色素 瘤的诊断率为90.6%(29/32),但在小肿 瘤、弥漫生长、少量或无色素、伴有大 量细胞坏死的大肿瘤者,信号强度不典 型,诊断较为困难,需要借助其他检查 方法。

Objective The relationship between mri signal characteristics of 32 cases (32 eyes) choroidal melanoma and the pathologic and intraorbital spread was analyzed. Methods A retrospective study was performed on 32 patients (32 eyes) of choroidal melanoma patients admitted to tianjin eye hospital from September 2003 to March 2010. Results In 32 cases of choroidal melanoma, 29 cases showed high signal and T2W low signal in T1W1. In 3 cases, T1W1 showed moderate signal and T2W1 showed low signal (2 cases of the ciliary body and the anterior choroid were all mixed with retinal subretinal and vitreous hemorrhage). 1 case of spindle cell type, with exudative retinal detachment, may be caused by the hemorrhage of the retina and vitreous body, and the hemorrhage of the tumor accompanied by a large number of tumor cell necrosis, and the signal characteristics are atypical.In one case, T1WI and T2WI were intermediate signals, possibly due to low melanin content. Conclusion Nuclear magnetism is characteristic of choroidal melanoma, but in small tumors or diffuse growth, the signal strength of low pigment is not typical, and other methods of examination are needed.

【关键词】脉络膜黑色素;核磁共振; 病理

【中图分类号】R773.4

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.08.009

前言

脉络膜黑色素瘤(choroidal melanoma,CM)由恶性黑色素瘤细胞 组成的神经外胚叶性肿瘤,组织来源于脉络膜基质内的黑色素瘤细 胞,是成人眼内最常见的恶性肿瘤。核磁共振检查是临床常用的一种 无创检查方法。它具有无辐射、多参数、多向成像、对软组织分辨率 高、无骨伪影干扰、扫描速度快等优点。对脉络膜黑色素瘤诊断率为 (66.7%)[1]。因为脉络膜黑色素瘤的发病率仅次于儿童的视网膜母细胞 瘤,所以早期能够借助核磁的特征进行诊断和治疗,能够使患者保留 眼球。