目的分析超声造影与多层螺旋 CT在肝细胞癌诊断中的应用。方法 回顾 性分析2015年4月-2017年12月间于我院就 诊的肝细胞癌患者的影像学资料，筛选 120例有完整超声造影及CT影像资料患者 作为研究对象，对比超声造影及CT动脉期 及门脉期增强特征及增强率、肝细胞癌表 现模式及其对血管形态、血管显像丰富程 度、坏死灶的评价。结果 超声造影及CT 检查时，动脉期、门脉期增强等级及肝 细胞癌表现模式比较差异无统计意义(P﹥ 0.05)；但超声造影动脉期增强率0-1及﹤0 比例、门脉期增强率﹤0比例均低于CT，门 脉期增强率0-1比例高于CT；且超声造影 所见条状不规则型血管形态比例、评价血 管显像丰富比例、圆孔状及片状坏死灶比 例高于CT，稀细型及无血管型血管形态比 例、评价血管丰富程度少量比例、无坏死 灶比例低于CT；且超声造影诊断阳性率高 于CT，上述差异有统计意义(P﹤0.05)。结 论 超声造影用于肝细胞癌临床诊断时， 在不同期相增强等级、表现模式上可获得 与CT相似表现形式，在评价血管形态、显 像丰富程度、阳性率上与CT比较亦具一定 优势。

Objective To analyze the application of contrast-enhanced ultrasound and multi-slice spiral CT in the diagnosis of hepatocellular carcinoma (HCC). Methods The imaging data of patients with HCC treated in the hospital between April 2015 and December 2017 were analyzed retrospectively. 120 patients with complete contrast-enhanced ultrasound and CT imaging data were selected as study subjects. The enhancement features and enhancement rates in aterial phase and portal phase, manifestations of HCC, assessment of vascular morphology, vascular imaging abundance and necrosis foci were compared between contrast-enhanced ultrasound and CT. Results There was no statistically significant difference in enhancement grade in arterial phase and portal phase or manifestations of HCC between contrast-enhanced ultrasound and CT (P>0.05). The ratios of enhancement rate of 0-1 and < 0 in arterial phase and enhancement rate < 0 in portal phase of contrast-enhanced ultrasound were lower than those of CT, while the ratio of enhancement rate in portal phase of 0-1 was higher than that of CT. The proportions of stripped irregular vascular morphology, rich vascular imaging and round-hole and patchy necrosis showed by contrast-enhanced ultrasound were higher than those by CT, while the proportions of thin and non-vascular vascular morphology, less vascular abundance and non necrosis were lower than those by CT. The positive rate of contrast-enhanced ultrasound was higher than that of CT (all P<0.05). Conclusion In the clinical diagnosis of HCC, the enhancement grade and manifestations of contrast-enhanced ultrasound in different phases are similar to those of CT. morphology can be obtained with CT in terms of at different phases. Compared with CT, contrastenhanced ultrasound has more advantages in assessing the vascular morphology, imaging abundance and positive rate.