目的探讨定量CT(QCT)和磁共 振成像(MR)在非酒精性脂肪肝(NAFLD)诊 断中的应用价值。方法 选取2016年2月 至2017年8月在我院治疗的NAFLD患者67例 (NAFLD组)，同时选取健康志愿者70例作 为对照组，两组均行QCT和MR扫描，其中 QCT采用校正后计算公式(Fat% QR)测量肝 脏脂肪含量，MR测量肝脏脂肪分数(Fat% MR)。结果 NAFLD组Fat% QR和Fat% MR分 别为(20.10±10.04)%和17.32(12.01， 23.10)%，明显高于对照组(P＜0.05)； NAFLD组男女患者Fat% QR和Fat% MR差异 比较无统计学意义(p＞0.05)；Fat% QR和 Fat% MR诊断NAFLD的ROC曲线下面积分别 为0.924和0.856，P＜0.05；Fat% QR截 断值为10.16%时，其诊断NAFLD的灵敏度 和特异度80.60%和94.29%；Fat% MR截断 值为14.05%时，其诊断NAFLD的灵敏度和 特异度73.10%和91.43%；Fat% QR和Fat% MR呈正相关(rs=0.722，P＜0.05)。结论 QCT和MR在NAFLD诊断中均有一定的应用价 值，其中QCT诊断效率较高。

Objective To investigate the application of quantitative CT (QCT) and magnetic resonance imaging (MR) in the diagnosis of nonalcoholic fatty liver (NAFLD). Methods 67 cases of NAFLD patients (NAFLD group) who were treated in our hospital from February 2016 to August 2017 were selected and 70 healthy volunteers were selected as the control group, QCT and MR scans were performed in all two groups,the fat content of the liver was measured by QCT corrected calculation formula (Fat% QR),the liver fat fraction (Fat% MR) was measured by MR. Results The Fat% QR and Fat% MR in NAFLD group were (20.10±10.04)% and 17.32 (12.01, 23.10)%, which were significantly higher than those in the control group (P<0.05). There was no significant difference in Fat% QR and Fat% MR between men and women in NAFLD group (P>0.05). The area under the ROC curve of Fat% QR and Fat% MR in diagnosis of NAFLD were 0.924 and 0.856, and P<0.05. When the cut-off value of Fat% QR was 10.16%, the sensitivity and specificity of the diagnosis of NAFLD were 80.60% and 94.29%. When the cut-off value of Fat% MR was 14.05%, the sensitivity and specificity of the diagnosis of NAFLD were 73.10% and 91.43%. Fat% QR was positively correlated with Fat% MR (rs=0.722, P<0.05). Conclusion QCT and MR have a certain value in the diagnosis of NAFLD, and the diagnostic value of QCT is high.