论著-头颈部
多层螺旋CT和MRI对肝癌患者经TACE治疗术后疗效评价的价值研究*
作者:戴 兵1 赵 华2
所属单位:1.河南省南阳市中心医院普通外科肝脏病区(河南 南阳 473000) 2.郑州大学第二附属医院(河南 郑州 450000)
PDF摘要
目的探究多层螺旋CT(MSCT)和 核磁共振成像(MRI)对肝细胞肝癌(HCC) 患者经导管肝动脉化疗栓塞(TACE)治疗 术后疗效评价的价值。方法 收集我院首 次行TACE治疗的56例HCC患者临床资料, 均于术后3个月行DSA、MSCT、MRI检查, 比较术后肿瘤残余或复发情况及肿瘤包膜 情况。结果 MSCT扫描与DSA标准组在有无 肿瘤残余或复发的显示率上比较,差异有 统计学意义(P<0.05);MRI扫描与DSA标准 组在有无肿瘤残余或复发的显示率上比 较,差异无统计学意义(P>0.05);MSCT与 MRI扫描判定TACE术后肿瘤残余或复发的 准确性及敏感性比较,差异均有统计学意 义(P<0.05);MSCT与MRI显示TACE术后肿 瘤包膜的检出率比较,差异有统计学意 义(P<0.05)。结论 MRI扫描对HCC患者经 TACE治疗术后肿瘤残余或复发的诊断准确 性及敏感性更高,可进一步指导临床治 疗。
Objective To explore the value of multi-slice CT (MSCT) and magnetic resonance imaging (MRI) in evaluating the postoperative efficacy of patients with hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE). Methods The clinical data of 56 HCC patients treated with TACE for the first time in our hospital were collected. All patients were given DSA, MSCT and MRI at 3 months after TACE. The postoperative tumors residual or recurrence and tumor capsule were compared. Results There were statistical significance in the displaying rate of presence or absence of tumors residual or recurrence between MSCT scan and DSA standard group(P<0.05). And there was no statistical significance in the displaying rate of presence or absence of tumor residual or recurrence between MRI scan and DSA standard group (P>0.05). There were significant differences in the accuracy and sensitivity of MSCT and MRI scans in determining the residual or recurrence of tumors after TACE (P<0.05). MSCT and MRI showed that the detection rate of tumor capsule after TACE was significantly different (P<0.05). Conclusion MRI scan has high diagnostic accuracy and sensitivity in diagnosis of postoperative residual or recurrent tumors of HCC patients after TACE, and it can further guide clinical treatment.
【关键词】多层螺旋CT;核磁共振成像; 经导管肝动脉化疗栓塞
【中图分类号】R735.7;R445.2;R445.3
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.08.028
前言
经导管肝动脉化疗栓塞(TACE)是利用导管注射化疗药物,使肿瘤 细胞直接暴露于高浓度化疗药物,可显著提高治疗疗效,并降低药物 毒副作用,现已成为治疗无法手术切除的肝细胞肝癌(HCC)患者的首 选方法。但TACE也无法使所有病灶完全坏死,肿瘤平均坏死率仅为 22%~72%[1]。因此,术后及时客观、理性评价TACE疗效至关重要。本 研究针对HCC患者经TACE治疗术后疗效的影像学评价进行深入回顾性分 析,比较多层螺旋CT(MSCT)和核磁共振成像(MRI)评价HCC患者经TACE 治疗术后疗效的价值。
中国CT和MRI杂志
第16卷, 第 8 期
2018年08月
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