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CT平扫与三期增强扫描对肺结节的诊断价值分析

作者:韩文彬 左 稳 陈竹碧 黄 琦 罗 颖

所属单位:四川宜宾市第一人民医院放射科(四川 宜宾 644000)

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摘要

目的探究CT平扫与三期增强扫 描在对肺结节的诊断中的应用价值。方 法 采用回顾性分析的方法对我院2016年6 月-2017年5月收治的56例患者进行研究分 析,56例患者入院后两周内都行CT平扫和 三期增强扫描,并经手术、病理检查进行 确诊为肺部结节性病变。结果 51例患者 中良性结节组26例和恶性结节组30例;CT 平扫良、恶性肺结节平均CT值比较,差异 无统计学意义(P>0.05);CT增强扫描60s 良、恶性肺结节的平均CT值比较,差异 存统计学意义(P<0.05),增强扫描15s、 30s所测的CT值比较均无统计学意义(P> 0.05)。以最大CT净增值20~60HU为恶性 结节,测得CT三期增强扫描对恶性结节诊 断的敏感性为92.86%、特异性为86.73%、 诊断准确性为81.46%。结论 CT平扫与三 期增强扫描在肺结节中具有较高的诊断准 确性,且对良性和恶性具有一定的鉴别诊 断价值。

Objective To investigate diagnostic value of CT plain scan and Tri-phase Enhancement scan in pulmonary nodules. Methods Used to analyze 56 patients our hospital from 2016 May-2017 June were selected to study by A retrospective analysis. Patients were treated with CT plain and three enhanced scan for two weeks after admission, and were diagnosed as pulmonary nodular lesions by surgical and pathological examination. Results There were 26 cases of benign nodules patients and malignant nodules patients in 51 cases. Comparing the average CT value by CT plain, there was no difference between benign nodules and malignant nodules (P>0.05), and compared with benign nodules, the average CT value of malignant pulmonary nodules by CT enhanced scan 60s benign was alleviated significantly (P<0.05). There was no statistically significant difference between the CT values of enhanced scan 15s and 30s (P>0.05). The CT added value between 20-60 HU was treated as malignant nodules. The sensitivity of the CT three phase enhanced scan to the diagnosis of malignant nodules was 92.86%, the specificity was 86.73%, and the diagnostic accuracy was 81.46% by measuring maximum net value of CT between 20-60HU of malignant nodule. Conclusion CT plain scan and three phase enhanced scan have high diagnostic accuracy in pulmonary nodules, and have certain differential diagnosis value for benign and malignant.

【关键词】CT;平扫与增强扫描;肺结节;鉴别诊断

【中图分类号】R734.4;R445.3

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.08.016

前言

肺结节属于多系统多器官的肉芽肿性疾病,病因尚不明确,常侵 犯肺、双侧肺门淋巴结、眼、皮肤等器官,其中以胸部受侵为主,其 受侵率高达80%~90%[1-2]。肺结节的临床症状和体征随着其起病的缓 急以及累及器官的多少而改变。胸内结节病早期常无明显症状和体征 出现。临床上对肺结节的诊断方法包括活体组织检查、支气管肺泡灌 洗液检查、经纤维支气管镜肺活检(TBLB)等,主要的影像学辅助诊断 方法为X线检查、胸部计算机体层扫描(CT)检查[3-6]。而有相关研究报 道[7],普通X线胸片对结节病诊断的正确率仅有50%。因此,近年来CT 在临床上对结节病的诊断方面的应用不断增加,但传统CT检查对于肺 结节中存在同种病中的不同影像表现和不同病的类似影像表现无法 进行区分,在大量的数据研究中也证实了这个观点。有相关资料显 示[8],CT增强扫描对结节病的类型、肺间质病变的程度和淋巴结肿大 的情况进行正确估计,且其对肺间质病变的诊断更为精确。为此,我 院采用CT平扫与三期增强扫描对患者进行检查,旨在探讨其在肺结节 的诊断中的应用价值,现报道如下。