摘要
目的评价双能量CT碘含量对正 常人肺实质首过血流灌注的定量价值。方 法 回顾性分析了心肺检查正常的15例患 者的首过肺实质血流灌注图像,并进行碘 含量的测定,对肺部不同区域的碘含量值 进行统计学分析。结果 同侧肺相同水平 位置腹侧和背侧肺实质血流灌注碘含量值 有显著的统计学差异,腹侧的血流灌注碘 含量均值低于背侧;左右侧肺相同位置区 域肺实质血流灌注碘含量值大部分有统计 学差异,左肺的肺实质血流灌注碘含量均 值高于右肺(P>0.05)。结论 肺实质首过 血流灌注的碘含量值可以敏感的反应肺实 质不同区域的血流灌注差异。
Objective To evaluate the value for quantitative analysis of the iodine concentration in pulmonary parenchymal with dual-energy CT perfusion imaging. Methods 15 patients without cardiac and pulmonary abnormality were accepted the dual-energy CT scanning. The data was post-processed on Siemens workstation to obtain PBV images, the iodine concentrate were calculated, which of the different area in pulmonary parenchymal were analyzed. Results Mean of iodine content in the ventral was significantly lower than the ipsilateral dorsal lung at same horizontal position; Meanwhile, the mean of iodine content in the left was higher than the right lung at the same horizontal position, however there were no significant differences between the two regions (P>0.05). Conclusion The iodine concentrate of PBV is sensitive to the perfusion difference of the pulmonary parenchymal with dual-energy CT perfusion imaging.
【关键词】肺灌注;碘含量;计算机体层成像;双能
【中图分类号】R322.3+5
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.08.014
前言
临床上,肺实质的血流灌注异常通常应用Tc标记的巨聚白蛋白核 素灌注扫描来评估。但核素肺灌注扫描存在扫描时间长,空间分辨率 低和不能开展临床急诊检查等缺陷。因而双能量CT肺灌注成像近期成 为肺灌注研究的热点,它是在肺动脉CT血管成像的基础上,利用碘对不 同能量X线的吸收不同,获得碘在双肺的分布图,从而反映肺组织的血 流灌注信息。双能量CT一次扫描就能提供肺栓塞相关的解剖结构及功 能性肺灌注的信息。近期国内外发表的双能量CT肺灌注成像文章均关 注在肺灌注对于肺栓塞诊断的临床价值[1-6]。而本文试图通过双能量CT 肺灌注扫描,测量造影剂首次通过肺实质的碘含量,定量分析正常人 肺实质静态灌注下肺部不同区域的碘含量差异,确立肺实质灌注碘含 量的范围,为双能CT肺灌注扫描诊断肺部疾病的肺实质灌注异常奠定 基础。
中国CT和MRI杂志
第16卷, 第 8 期
2018年08月
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