目的 探究磁共振弥散张量成像 (diffusion tensor imaging, DTI)在弥 漫性轴索损伤(diffuse axonal injury, DAI)中的应用价值。方法 回顾性分析 2014年3月-2017年3月我院收治的36例DAI 患者(DAI组)的临床资料，选择36例健康 志愿者(对照组)进行DTI检查。分析DAI组 患者的影像学图像特点，比较两组感兴 趣区(region of interest, ROI)(胼胝体 压部、内囊、额叶白质、丘脑)的各向异 性分数(FA)值和表观弥散系数(apparent diffusion coefficient, ADC)值的差 异。结果 DAI组ROI(胼胝体压部、内囊、 额叶白质、丘脑)的FA值和ADC值均明显低 于对照组(P﹤0.05)。结论 DTI能够客观反 映DAI患者的脑白质损伤情况，对DAI的诊 断和与预后评估均有较高的敏感性。

Objective To explore the application value of diffusion tensor imaging (DTI) in diffuse axonal injury (DAI). Methods The clinical data of 36 patients with DAI (DAI group) treated in our hospital from March 2014 to March 2017 were retrospectively analyzed, and 36 healthy volunteers (control group) were examined by DTI. Image features of patients with DAI were analyzed. Fractional anisotropy (FA) values and apparent diffusion coefficient (ADC) values of region of interest (ROI) (the splenium of the corpus callosum, the internal capsule, frontal white matter, thalamus) were compared between the two groups. Results FA and ADC values of ROI (the splenium of the corpus callosum, the internal capsule, frontal white matter, thalamus) in DAI group were significantly lower than those in the control group (P<0.05). Conclusion DTI can objectively reflect the white matter damage in patients with DAI, which is of high sensitivity in the diagnosis of DAI and evaluation of the prognosis.