论著-头颈部
MRI技术用于脑胶质 瘤患者外科手术时 对麻醉的影响
作者:赵 方1 银 瑞2
所属单位:1.河南省南阳市中心医院麻醉科 (河南 南阳 473009) 2.河南省南阳市中心医院胸外科 (河南 南阳 473009)
PDF摘要
目的 探讨磁共振成像(MRI)技术 用于脑胶质瘤患者外科手术时对麻醉的影 响。方法 选取2016年10月至2017年10月 我院神经外科收治的脑胶质瘤患者150例 为研究对象,其中拟在全身麻醉下应用 MRI技术行幕上开颅肿瘤切除术的患者50 例(研究组),同期行颅内肿瘤常规手术患 者100例(对照组),记录两组手术一般情 况及手术不同时段[麻醉诱导后(T0)、开 颅后60min(T1)、扫描前即刻(T2)、扫描 后15min(T3)、扫描后30min(T4)、扫描 后1h(T5)、手术结束时(T6)]平均动脉压 (mean arterial pressure, MAP)、心率 (heart rate, HR),同时记录两组手术前 后肿瘤体积、切除体积、肿瘤切除率及 并发症发生率。结果 研究组手术准备时 间、手术时间、麻醉时间较对照组明显 延长(P<0.01);研究组T2-T6时段MAP、 T2-T5时段HR均高于对照组(P<0.05); 研究组术后肿瘤体积小于对照组,切除体 积、肿瘤切除率大于对照组(P<0.01); 两组并发症发生率比较差异无显著性(P> 0.05)。结论 脑胶质瘤患者在外科手术中 应用MRI技术可提高肿瘤切除率,但手术 时间、麻醉时间较常规手术明显延长, 在MRI扫描后至手术结束时MAP、HR波动 大,应加强监测,对于伴严重心脏疾病患 者选择此项技术应慎重。
Objective To explore the effects of magnetic resonance imaging (MRI) technique on anesthesia in surgery of glioma patients. Methods 150 cases of patients with glioma admitted to the department of neurosurgery of our hospital from October 2016 to October 2017 were selected for the study, including 50 cases scheduled to craniotomy performed on the screen of MRI technique under general anesthesia (the study group) and 100 cases with conventional surgery for intracranial tumors at the same period (the control group). The operation general situation, and the mean arterial pressure (MAP) and heart rate (HR) at different periods of surgery [after anesthesia induction (T0), 60min after craniotomy(T1), immediately before scanning (T2), 15min after scanning (T3), 30min after scanning (T4), 1h after scanning (T5), at the end of operation (T6)] were recorded in the two groups, and the tumor volume, resection volume, tumor resection rate and the complications incidence rate were recorded in the two group before and after surgery. Results The preparation time, operative time and anesthesia time in the study group were significantly longer than those in the control group (P<0.01). The MAP from T2 to T6 time periods and the HR from T2 to T5 time periods in the study group were all higher than those in the control group (P<0.05). The postoperative tumor volume in the study group was smaller than that in the control group while the resection volume and tumor resection rate were higher than those in the control group (P<0.01). There was no significant difference in the incidence rate of complications between the two groups (P>0.05). Conclusion The application of MRI technique in the surgery of glioma patients can improve the tumor resection rate, but the operative time and anesthesia time are obviously longer than the conventional operation. From the MRI scanning to the end of operation, the MAP and HR have great fluctuations, which should be strengthened monitoring. And for patients with severe heart disease, this technique should be carefully chosen.
【关键词】MRI技术;脑胶质瘤;外科手 术;麻醉
【中图分类号】R445.2;R739.41
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2018.04.005
前言
脑胶质瘤也称为脑干肿瘤,约占颅内肿瘤总数的37%~52%,外科 手术为其首选治疗方案,而术中精确定位手术部位,有效切除瘤体 是提高手术质量关键[1]。术中磁共振成像技术(intraoperative MRI, iMRI)已成为神经外科领域中重要的辅助技术,不仅可精确引导手术进 程,精确手术定位,同时提高临床疗效及安全性,若术中发现残留, 可继续进行肿瘤切除,目前已在成人、未成年人脑胶质瘤神经外科手 术中开展应用[2]。但同时MRI对机体及周围环境也会产生一定影响,当 磁场较强时会产生感应电效应,血液在磁场中也产生电动力,组织中 出现感应电流引起血流动力学波动,因此MRI技术的应用也给麻醉管理 带来新要求及挑战[3]。本文纳入2016年10月至2017年10月我院神经外 科收治的脑胶质瘤患者150例,分析术中应用MRI技术对其麻醉及手术 效果的影响,结果如下。
中国CT和MRI杂志
第16卷, 第 4 期
2018年04月
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