论著-头颈部
动脉瘤应用64排 CTA检查的临床研 究
作者:汤 韬1 王 晓2
所属单位:1.河南省南阳市第二人民医院神经 外科 (河南 南阳 473000) 2.河南省南阳市第二人民医院放射 科 (河南 南阳 473000)
PDF摘要
目 的 研究64排CT血管成像 (CT angiography,CTA)检查动脉瘤 (intracranial aneurysm,IA)的临床应 用。方法 回顾性分析我院收治的49例 自发性蛛网膜下腔出血患者的64排CTA影 像资料,采用容积再现、最大密度投影 图像后处理手段对所获取影像资料进行 分析,并以数字减影血管造影为“金标 准”,计算64排CTA的灵敏度、特异度、 准确率、阳性预测值、阴性预测值、一 致性。结果 49例SAH患者中,经DSA共检 出45例52个IA,其载瘤动脉依次为大脑 前动脉5个、大脑中动脉7个、大脑后动 脉2个、前交通动脉16个、后交通动脉3 个、颈内动脉C1段17个、椎动脉2个; 经64排CTA共检出46例55个IA,载瘤动 脉依次为大脑前动脉5个、大脑中动脉6 个、前交通动脉16个、后交通动脉6个、 颈内动脉17个、椎动脉5个,64排CTA 检查诊断IA的灵敏度为100.00%、特异 度75.00%、准确率93.87%、阳性预测值 97.72、阴性预测值60.00%,一致性为 0.846,提示一致性良好。结论 64排CTA 应用于动脉瘤的临床检查,不仅价格相 对低廉、安全性佳,亦能清晰反应IA形 态、位置、与周围结构的毗邻关系。
Objective To study the clinical application of 64-slice CTA in the diagnosis of intracranial aneurysms. Methods The 64-slice CTA imaging data of 49 patients with spontaneous subarachnoid hemorrhage in our hospital were analyzed retrospectively. The imaging data were analyzed by volume rendering and maximum intensity projection, and the sensitivity, specificity, accuracy, positive predictive value, negative predictive value and consistency of 64 -slice CTA were calculated with digital subtraction angiography as the golden standard. Results In 49 patients with SAH, 52 IA in 45 cases were detected by DSA, and parent arteries included 5 anterior cerebral artery (ACA), 7 middle cerebral artery (MCA), 2 posterior cerebral artery (PCA), 16 anterior communicating artery (AComA), 3 posterior communicating artery (PComA), 17 internal carotid artery C1 segments (ICA) and 2 vertebral artery (VA). A total of 55IA in 46 patients were detected by 64 -slice CTA, and parent arteries included 5 ACA, 6 MCA, 16 AComA, 6 PComA, 17 ICA and 5 VA. The sensitivity, specificity, accuracy, positive predictive value, negative predictive value and consistency (kappa) of 64 -slice CTA in the diagnosis of IA were 100.00%, 75.00%, 93.87%, 97.72%, 60.00% and 0.846 respectively, suggesting good consistency. Couclusion 64-slice CTA in IA is not only cheap and safe but also can clearly reflect the shape, location and the adjacent relationship with the surrounding structure of IA.
【关键词】动脉瘤;64排CTA;临床研究
【中图分类号】R445.3;R743.4
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2018.04.046
前言
动脉瘤(intracranial aneurysms,IA)系脑动脉局限性异常扩张所 致,也是导致自发性蛛网膜下腔出血(subarachnoid hemorrhage,SAH) 的致病因素,导致患者出现脑血管痉挛、脑水肿、脑梗死及脑积水等 多种恶性病理生理改变,首次SAH发作其致死致残率高达30%,但若再 次复发,该比例可上升至70%[1]。但在临床诊断时,仅部分IA体积较 大患者或可因瘤体扩张、压迫等出现单盲眼及动眼、外展、面神经麻 痹等症状、极大多数的IA患者在瘤体未出血前并无显著症状及体征, 因此,如何在早期有效诊断并制定合理规范化治疗方案以降低不良预 后风险尤为重要[2]。鉴于此,现回顾性分析我院收治的IA患者的64排 CTA、DSA影像资料,旨在为64排CTA诊断IA提供高价值临床实践经验, 具体报道如下。
中国CT和MRI杂志
第16卷, 第 4 期
2018年04月
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