目的 探讨双源CT心肌灌注检测 评价冠状动脉临界病变的临床价值。方 法 搜集33例(共41个冠状动脉病变)双 源CT冠状动脉成像诊断为临界病变的患 者，所有患者均于一周内经冠状动脉造 影证实，并行血流储备分数(FFR)检测。 将41个冠状动脉临界病变按FFR检测值分 为FFR<0.80组和FFR≥0.80组；按照标准 A(两个或以上节段心肌灌注异常)、B(一 个或以上节段心肌灌注异常)进行心肌灌 注分析。结果 FFR<0.80和FFR≥0.80两组 间心肌灌注检测A、B标准均有统计学差异 (标准A：χ2 =11.303, P=0.001；标准B： χ2 =12.812, P=0.000)；应用ROC曲线分 析显示心肌灌注检测标准A和标准B对心 肌灌注检测均有统计学意义(AUCA=0.734, P=0.017; AUCB=0.798，P=0.002)，采用 标准B诊断效能较高。结论 心肌灌注检测 有助于双源CT“一站式”评价冠状动脉临 界病变。

Objective To study the the clinical value of dual-source CT myocardial perfusion test in the evaluation of cononary intermediate lesions. Methods 33 cases (41 sites) of coronary intermediate lesions underwent dual-source CT coronary angiography and were confirmed by conventional coronary angiography and Fractional Flow Reserve(FFR) test within one week. According to FFR value, 41 intermediate lesions were divided into two groups: FFR<0.80 group and FFR≥0.80 group. Dual-source CT myocardial perfusion test of all the cases was performed according to the standard A(≥2 segments myocardium involved) and standard B(≥1 segment myocardium involved). Results There were statistically significant differences in dual-source CT myocardial perfusion between two groups with standard A(χ2 =11.303, P=0.001) and standard B(χ2 =12.812, P=0.000). ROC curve analysis indicated that both criteria (standard A and standard B) were statistically significant for myocardial perfusion test (AUCA=0.734, P=0.017, AUCB=0.798, P=0.002) and standard B had higher diagnostic efficacy. Conclusion Myocardial perfusion test could be helpful for Dual-source CT in "one-stop" evaluation of coronary intermediate lesions.