目的 探究多层螺旋CT(multislice spiral CT, MSCT)在肺磨玻璃 结节(ground-glass opacity, GGO)诊 断中的应用。方法 回顾性分析2016年8 月-2017年9月于我院行CT引导下穿刺活 检或手术病理确诊的58例GGO患者的临床 资料及MSCT检查影像学资料，对比分析 良性病变、不典型腺瘤样增生(atypical adenomatous hyperplasia,AAH)及恶性病 变三者间是否存在差异。结果 58例GGO中 单纯型GGO者23例(良性12例，AAH6例， 恶性5例)，混合型GGO者35例(良性5例， 恶性30例)；良性GGO、AAH、恶性GGO的 发病年龄及病灶大小比较，良性GGO年龄<aah<恶性ggo，恶性ggo病灶大小>良性 GGO>AAH，差异有统计学意义(P>0.05)； 良性GGO、AAH、恶性GGO患者的MSCT影 像学征象中病灶形状、边界清晰度、边 缘形态及病灶支气管充气征、胸膜凹陷 征、血管集束征比较，差异有统计学意义 (P>0.05)。结论 GGO含多种疾病，不同类 型GGO的MSCT征象表现不同，MSCT对GGO的 良恶性鉴别具较高诊断价值，值得进一步 推介。

Objective To explore the application of multi-slice spiral CT (MSCT) in the diagnosis of pulmonary ground-glass opacity (GGO). Methods The clinical data and MSCT imaging data of 58 cases of GGO patients confirmed by CT-guided biopsy or surgical pathology in our hospital from August 2016 to September 2017 were retrospectively analyzed. The differences between benign lesions, atypical adenomatous hyperplasia (AAH) and malignant lesions were compared and analyzed. Results Among the 58 cases of GGO, there were 23 cases of simple GGO (12 benign cases, 6 AAH cases and 5 malignant cases) and 35 cases of mixed GGO (5 benign cases, 30 malignant cases). The age and lesion size of benign GGO, AAH and malignant GGO were that benign GGO age<aahbenign GGO>AAH (P>0.05). There were significant differences in the MSCT imaging features (lesion shape, boundary definition, marginal morphology and lesion bronchoalveolar inflated sign, pleural indentation and vessel convergence sign) among the benign GGO, AAH and malignant GGO (P>0.05). Conclusion GGO contains a variety of diseases, and different types of GGO have different performance of MSCT signs, and MSCT has high diagnostic values for the benign or malignant GGO, therefore it is worthy of further referral.