目的 探讨PET-CT在路易体痴呆 患者临床诊断中的应用价值及影像学特征 表现。方法 回顾性分析2013年1月-2017 年5月期间入我院就诊的21例路易体痴呆 患者病例资料，所有患者均常规予以MRI 检查及PET-CT显像诊断，分析其影像学特 征。结果 PET-CT结果显示：DLB患者PETCT显像表现为：双侧枕顶叶皮质以及颞上 回前部葡萄糖代谢明显降低；前扣带回及 中央沟邻近皮质局部葡萄糖代谢轻度降 低。且AUC=9.865时，PET-CT诊断DLB灵 敏度及特异度分别为90.47%和95.23%， OR(95%CI)为1.535(1.025-3.166)，且明 显较常规MRI诊断灵敏度和特异度高，差 异显著(P<0.05)。结论 PET-CT用于DLB诊 断具有特征性影像学表现，且具有较高灵 敏度和特异度。

Objective To investigate the clinical value and imaging features of PET-CT in the diagnosis of dementia with Lewy bodies(DLB). Methods The clinical data of 21 DLB patients admitted to our hospital from January 2013 to May 2017 were retrospectively analyzed. All patients were diagnosed by MRI and PET-CT, and their imaging features were analyzed. Results PET-CT imaging of DLB patients showed: glucose metabolism decreased significantly in bilateral occipital parietal cortex and anterior temporal gyrus, and regional glucose metabolism decreased slightly in anterior cingulate cortex and central sulcus adjacent cortex. At AUC=9.865, the sensitivity and specificity of PETCT in diagnosis of DLB were 90.47% and 95.23%, and OR (95%CI) was 1.535 (1.025- 3.166), and the sensitivity and specificity of PET-CT were significantly higher than those of conventional MRI (P<0.05). Conclusion PET-CT for DLB diagnosis has the characteristic imaging findings, and has high sensitivity and specificity.