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MRI在脑胶质瘤诊断及治疗随访中应用

作者:李振玉1 张国栋2

所属单位:1.河南省新乡市中心医院影像中心 磁共振室 (河南 新乡 453000) 2.河南省新乡市中心医院神外二科 (河南 新乡 453000)

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摘要

目的 探讨MRI在脑胶质瘤诊断及 治疗随访中的应用价值。方法 回顾性分 析2008年3月-2011年10月我院收治的32例 经手术病理证实的脑胶质瘤患者的临床 资料,所有病例患者均进行MRI诊断,观 察患者MRI表现及肿瘤病理类型,患者术 后进行随访,分析患者治疗随访后其MRI 平扫和增强扫描影像学表现,以探讨MRI 在脑胶质瘤治疗随访中的应用价值。结果 32例病例患者中星形细胞瘤18例(包含毛 细胞型星形细胞瘤,弥漫型星形细胞瘤以 及胶质母细胞瘤等);少突胶质瘤6例,室 管膜肿瘤5例,脉络丛乳头状瘤3例,各类 型脑胶质瘤其MRI影像学表现各异。治疗 后随访观察发现18例表现为反应性强化, 5例残余肿瘤,9例复发,MRI表现亦各不 相同。结论 MRI在脑胶质瘤诊断的中价值 较高,治疗随访中可依据病灶影像学征象 不同加以判断预后状况。

Objective To investigate the application value of MRI in the diagnosis and treatment follow-up of gliomas. Methods The clinical data of 32 patients with gliomas confirmed by surgery and pathology in our hospital between March 2008 and October 2011 were retrospectively analyzed. All cases were diagnosed by MRI, and the MRI manifestations and pathological types of the patients were observed. Patients were followed up after operation. The manifestations of MRI plain scan and enhanced scan were analyzed to explore the application value of MRI in the follow-up of gliomas after treatment. Results In32 cases, there were 18 casesof astrocytomas (including pilocytic astrocytoma, diffuse astrocytoma and glioblastoma etc.). 6 cases of oligodendrogliomas, 5 cases of ependymomas and 3 cases of choroid plexus papilloma. MRI imaging findings of various types of gliomas were different.After treatment, follow-up found that 18 cases showed reactive enhancement, 5 cases had residual tumor and 9 cases had recurrence, and the MRI manifestations were different. Conclusion MRI is of high value in the diagnosis of gliomas, and the prognosis of the patients can be judged according to the different imaging findings.

【关键词】脑胶质瘤;MRI;随访

【中图分类号】R651.1

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.05.003

前言

脑胶质瘤为临床少见的颅内恶性肿瘤,以神经胶质细胞弥漫性生 长为典型特征的原发性肿瘤,临床具有浸润性生长、边界不清晰及容 易复发的特征,虽其病理类型与颅内单发胶质瘤类似,但其病灶数量 多,病灶可累及范围广,存在高漏诊及误诊率,且预后效果差,而临 床及时准确诊断可为临床医师制定手术方案提供重要参考[1]。现阶段 临床对其治疗以外科手术、放化疗为主,但治疗中因受其自身病理特 点及手术治疗范围等因素的影响,通常难以将其完全切除,且患者术 后复发率较高,因而患者治疗后有必要对其进行有效随访复查,以确 保患者治疗后取得良好预后效果,现阶段对患者手术切除程度及术后 修复征象进行评估是评价脑胶质瘤患者预后效果及复发情况的重要主 措[2-3]。目前随着医疗水平及影像学技术不断进展,MRI在疾病诊断中 日益被广泛应用,而王涛[4]研究中认为MRI增强扫描可对病灶位置、数 目、肿瘤大小以及病灶周边状况进行全方面的探查,但目前有关MRI在 脑胶质瘤治疗随访中的应用价值相关文献较少涉及,笔者于本文展开 回顾性分析,现将结果简单报告如下。