目的 分析低剂量、低速率多 排CT灌注成像在乳腺良恶性肿块鉴别 中的应用价值。方法 将我院2012年7 月-2015年4月收治的68例疑似乳腺病变 的患者作为研究对象，均接受低剂量、 低速率多排CT灌注扫描，分析多排CT灌 注成像鉴别乳腺良恶性肿块的准确性， 总结其CT影像学特点。结果 本组68例 乳腺病变患者，病理证实为良性31例， CT平扫检出10例，检出率为32.26%；病 理证实为乳腺癌37例，CT平扫检出14 例，占37.84%，CT平扫检出良恶性乳腺 病变所占比例对比差异无统计学意义 (P>0.05)；乳腺良性病变患者多为非肿 块性、边缘清晰，且无分叶，强化多均 匀；乳腺癌患者常见肿块征象，边缘不 清晰，可见毛刺，分叶，强化多不均 匀；乳腺癌患者CT灌注参数BF、BV、PS 值均高于良性乳腺病变者，对比差异有 统计学意义(P<0.05)。结论 低剂量CT灌 注成像可清晰显示乳腺良恶性肿块形态 学及血流灌注特点，客观性好，重复性 高，鉴别诊断价值高。

Objective To analyze the application value of low-dose and low-rate multislice CT perfusion imaging in differentiating benign and malignant breast masses. Methods 68 patients with suspected breast lesions treated in our hospital from July 2012to April 2015 were taken as the research objects. All of them received low-dose and low-rate multi-slice CT perfusion scan. The accuracy of multi-slice CT perfusion imaging in differentiating benign and malignant breast masses was analyzed. The CT imaging features were summarized. Results In the 68 cases of patients with breast lesions, 31 benign cases were confirmed by pathology and 10 cases detected by CT plain scan. The detection rate was 32.26%. 37 cases of breast cancer were confirmed by pathology and 14 cases were detected by CT scan, accounting for 37.84%. The differences in the proportions of CT scan in the detection of benign and malignant breast lesions were not statistically significant (P>0.05). Most of the benign breast lesions in patients were non-mass, with clear edge and without lobulation. Most enhancement was homogeneous; The common signs of patients with breast cancer were unclear edge, visible burr, lobulation and most enhancement was inhomogeneous. CT perfusion parameters such as BF, BV and PS values of patients with breast cancer were higher than those of patients with benign breast lesions (P<0.05). Conclusion Low-dose CT perfusion imaging can clearly show the morphology and blood flow characteristics of benign and malignant breast masses. The objectivity is good, repeatability is high and the value of the differential diagnosis is high.