摘要
目的 探讨增强MRI与超声造影用 于评估高强度聚焦超声(HIFU)治疗子宫肌 瘤的消融情况。方法 回顾性分析我院60 例HIFU治疗子宫肌瘤患者(肌瘤60个)的临 床病历资料,并于治疗前及治疗后1 d分 别采用MRI、超声造影检查。统计两组图 像质量评分、治疗前后肌瘤体积等。结 果 增强MRI图像质量评分、术后无灌注区 体积及平均消融率分别为(3.9±0.3)分、 (81.9±82.7)cm3、(80.7±18.4)%与超声 造影(2.0±0.7)分、(65.7±66.1)cm3、 (71.5±19.4)%比较,差异具有统计学意 义,P<0.05;增强MRI肌瘤图像显示总分 为114分明显高于超声造影62分,差异具 有统计学意义,P<0.05。应用增强MRI扫 描检查可清晰显示肌瘤边界、大小及其与 周围组织的关系;然超声造影显示边界较 模糊,10例患者无法确定肌瘤边界。结论 应用增强MRI可较好地评估HIFU治疗子宫 肌瘤的消融程度,从而为临床治疗方案的 选择及预后判断提供有力依据。
Objective To investigate the ultrasound contrast-enhanced MRI and high intensity focused ultrasound for assessment (HIFU) ablation treatment of uterine fibroids. Methods A retrospective analysis of our hospital 60 cases of HIFU treatment of uterine fibroids (myoma 60) clinical medical records, and before and after treatment 1 d respectively MRI, ultrasound imaging. Statistical two sets of image quality scores before and after treatment fibroid volume and so on. Results Enhanced MRI image quality score, patients without perfusion volume and average ablation rate was (3.9±0.3) points, (81.9±82.7) cm3 , (80.7±18.4)% and ultrasound contrast (2.0±0.7) points , (65.7±66.1) cm3 , (71.5±19.4)%, the difference was statistically significant, P<0.05, enhanced MRI fibroids total score of 114 points image display ultrasound contrast significantly higher than 62 points, the difference was statistically significant, P<0.05. Applications enhanced MRI scan can clearly show the relationship between fibroids border, size and with the surrounding tissue; however ultrasound contrast display blurry boundary, 10 patients could not be determined fibroids border. Conclusion Enhanced MRI can better assess the extent of HIFU ablation treatment of uterine fibroids, thus providing a strong basis for the selection of clinical prognosis and treatment options.
【关键词】增强MRI;子宫肌瘤;高强度 聚焦超声;超声造影
【中图分类号】R445.2;R737.33
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2016.12.034
前言
子宫肌瘤是育龄妇女人群中常见良性肿瘤,目前临床治疗方式主 要为药物和手术切除子宫等,然手术为有创性治疗,且术后并发症较 多[1]。高强度聚焦超声(HIFU)是一种非侵入性的局部治疗技术,其主 要是利用超声波具有的能量沉积性及组织穿透性,将体外发生的超声 波聚焦到生物体内病变组织处,并利用超声热效应及空化效应等来使 组织内温度瞬间上升至60℃以上,从而可快速使直径2mm以下血管闭 塞,并使组织凝固性坏死等[2]。这种方法对组织损伤很小,甚至无损 伤。目前超声或MRI等影像学评价HIFU治疗子宫肌瘤消融情况逐渐增 加,本次为探讨增强MRI与超声造影应用于HIFU治疗子宫肌瘤的消融情 况,特选择我院所收治60例子宫肌瘤患者实施研究,如下。
中国CT和MRI杂志
第14卷, 第 12 期
2016年12月
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