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3.OT场强磁共振应 用MRA血管成像与 3D-ASL脑灌注成像 技术在诊断缺血性 脑血管疾病中的应 用

作者:郭慧敏1 杨晓光2 王泽峰2

所属单位:1.内蒙古医科大学附属医院脑电图 室 (内蒙古 呼和浩特 015000) 2.内蒙古医科大学附属医院影像诊 断科 (内蒙古 呼和浩特 015000)

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摘要

目 的 3.OT磁共振血管成像 (MRA)与三维动脉自旋标记技术(3D-ASL) 脑灌注成像技术在诊断缺血性脑血管疾 病中的应用。方法 选取我院2014年7月 至2015年7月60例缺血性脑血管疾病患 者为研究对象,分别采用3.OT场强磁共 振应用MRA血管成像与CD-ASL脑灌注成 像技术诊断,观察MRA与3D-ASL诊断结 果,及对短暂性脑缺血发作、大面脑梗 死、小面积脑梗死诊断的一致性,并对 其图像进行分析。结果 3D-ASL诊断灵敏 度为93.33%、特异度为90.00%,均高于 MRA的70.00%、66.67%,有统计学意义 (P<0.05)。在15例短暂性脑缺血发作患 者中,11例诊断一致,4例诊断不一致; 4诊断不一致的患者经3D-ASL诊断为灌注 减低,但经MRA诊断显示为无异常。21例 大面脑梗死患者,经MRA与3D-ASL均一 致。在24例小面积脑梗死患者中,17例 诊断不一致,7例诊断一致。结论 3DASL诊断灵敏度、特异度均高于MRA,3DASL与MRA对大面积脑梗死的诊断一致性 较高,具有较好的临床应用价值。

Objective To explore the application of 3.0T magnetic resonance angiography (MRA) and three-dimensional arterial spin labeling (3D-ASL) cerebral perfusion imaging in the diagnosis of ischemic cerebrovascular disease. Methods Sixty patients with ischemic cerebrovascular disease admitted in our hospital between July 2014 and July 2015 were selected as the study subjects. 3.0T MRA and CD-ASL cerebral perfusion imaging were respectively used for diagnosis, and the results were observed. The consistency in the diagnosis of transient ischemic attack, large-area cerebral infarction, small-area cerebral infarction and images were analyzed. Results The diagnostic sensitivity and specificity of 3D-ASL (93.33%, 90.00%) were higher than those of MRA (70.00%, 66.67%) (P<0.05). In 15 cases with transient ischemic attack, the diagnosis of 11 cases were consistent while of 4 cases were not consistent, and the 4 cases, were diagnosed as perfusion decline by 3DASL. However, the diagnosis of MRA showed no abnormality. The diagnosis of MRA and 3D-ASL in 21 cases with large-area cerebral infarction were consistent. In 24 cases with small-area cerebral infarction, the diagnosis of 17 patients was not consistent while of 7 cases was consistent. Conclusion The diagnostic sensitivity and specificity of 3D-ASL are higher than those of MRA. The consistency of 3D-ASL and MRA in the diagnosis of large-area cerebral infarction is high.

【关键词】3.0T场强磁共振;MRA;3D ASL;缺血性脑血管疾病

【中图分类号】R743

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.12.012

前言

脑血管疾病致残率、死亡率均较高,其中缺血性脑血管病占70%- 80%[1]。缺血性脑血管病病因较为复杂,主要由脑供血血管狭窄、闭塞 等因素造成[2];常见的缺血性脑血管疾病主要包括短暂性脑缺血发作、 缺血性脑梗死。MRA是一种无创性显示血管的技术,无需对比剂,且随 着MRI设备、后处理技术不断地发展及3.OT场强磁共振应用,MRA的敏 感性、准确性不断增加[3]。3D-ASL可用于评价脑血流灌注情况,是近年 来发展的一种全新容积灌注扫描技术[4]。本研究选取我院2014年7月至 2015年7月60例缺血性脑血管疾病患者为研究对象,主要探讨了3.OT场 强磁共振应用MRA血管成像与3D-ASL脑灌注成像技术在诊断缺血性脑血 管疾病中的应用价值,现将结果报道如下。