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脑灰质异位的MRI平 扫及增强扫描特征 及价值分析

作者:白少君1 李 利2 张 崛1

所属单位:1.湖北省天门市第一人民医院CT室 2.湖北省天门市第一人民医院神经 外科 (湖北 天门 431700)

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摘要

目的 探讨脑灰质异位的MRI平扫 及增强扫描特征及价值,提高对脑灰质异 常的表现及临床特征的认识。方法 回顾 分析2009年9月至2012年9月经手术病理证 实的10例脑灰质异位患者,所有患者均进 行MRI平扫和增强扫描,分析其临床及影 像学表现。结果 脑灰质异位患者的MRI平 扫表现如下,MRI平扫T1、T2、FLAIR轴位 可见四叠体池偏左侧枕叶区域团片状混杂 信号影,病灶边界欠清楚,信号不均匀; MRI平扫IR T1序列可见四叠体池偏左侧枕 叶区域病灶显示更明显;MRI平扫eDWI序 列呈等信号,未见扩散受限。MRI平扫诊 断的确诊率达90%。MRI增强扫描轴位、冠 状位、矢状位,可见四叠体池偏左侧枕叶 区域病灶无明显强化。MRI增强扫描的确 诊率达100%。MRI增强扫描的确诊率高于 MRI平扫,诊断结果与临床病理诊断结果 相比,差异无统计学意义。结论 脑灰质 异位的MRI表现具有特征性,MRI在脑灰质 异位的诊断中具有非常高的应用价值,可 以作为脑灰质异位的重要检查方法。

Objective To study the characteristics and value of MRI scan and enhanced scan in heterotopic gray matter, and to improve the performance and clinical features of gray matter. Methods The clinical and imaging findings of 10 patients with heterotopic gray matter confirmed by surgery and pathology from September 2009 to 2012 were analyzed retrospectively. All patients underwent MRI plain scan and enhanced scan. Results The brain gray matter heterotopia patients MRI diagnosis results are as follows, T1, T2, flair axial visible quadrigeminal cistern partial left occipital lobe group piece like mixed signal, lesions were ill defined, inhomogeneous signal. MRI plain scan IRT1 sequence visible quadrigeminal cistern partial left occipital lobe lesions showed more obvious; MRI plain scan eDWI sequence showed signal, no restricted diffusion. The diagnosis rate of MRI plain scan was 90%. MRI scan axial, coronal, sagittal, visible partial quadrigeminal cistern left occipital lobe lesion showed no enhancement. The diagnostic rate of MRI enhanced scan was 100%. The diagnostic rate of MRI enhanced scan was higher than that of MRI plain scan, and the difference was not statistically significant compared with the results of clinical pathology. Conclusion MRI features of heterotopic gray matter in the brain, MRI has a very high value in the diagnosis of brain gray matter, and can be used as an important examination method of gray matter in the brain.

【关键词】脑灰质异位;磁共振成像

【中图分类号】R742.8;R445.2

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.12.011

前言

脑灰质异位症(gray matter heterot),简称GMH。在胚胎时期, 神经元在移行过程中受阻而聚集在室管膜和皮质之间,从而产生了 一种先天性畸形-脑灰质异位。脑灰质异位也可以跟其他中枢神经系 统其他畸形同时存在,成为智力和体力障碍的原因之一[1]。Rudolph Virchow是在Jungel报导1例异位病变后正式提出脑灰质异位这一用 语。   随着科技的进步,影像学扫描诊断技术也随之有所提高,自CT及 MRI等影像技术应用于临床以来,该病的检出率有了明显的提高,近年 来与脑灰质异位相关的报道也日益增多,同时MRI也成为本病的主要检 查方法和确诊手段[2]。本文回顾性的分析了2009年9月至2012年9月的 10例经临床病理证实的脑灰质异位患者的MRI平扫及MRI增强扫描的影 像资料,探讨MRI平扫及MRI增强扫描在脑灰质异位诊断中的价值。