目的 探讨MRI常规扫描、DWI及 血清CA125对卵巢肿块的定性诊断价值。 方法 收集76例卵巢肿块患者MRI及临床 资料。使用西门子1.5T超导磁共振机， 行常规矢状位T2WI、横轴位T1WI及抑脂 T2WI，DWI取b值为50、500、800s/mm2。 在西门子后处理工作站分析卵巢肿块的 信号特征，测量良、恶性肿瘤实性部分 的ADC值。结果 卵巢良性(非畸胎瘤)、 恶性肿瘤实性部分的ADC值差异有统计学 意义(P<0.05)；ROC曲线下面积0.904， 最佳诊断阈值为1.281×10-3mm2/s。MRI诊 断卵巢良、恶性肿块的敏感度为80.0%， 特异度为92.2%，约登指数为72.2%， Kappa值为0.729；MRI结合血清CA125诊 断卵巢良、恶性肿块的敏感度为88.0%， 特异度为94.1%，约登指数为82.1%， Kappa值为0.821。结论 MRI多序列扫描结 合ADC值定量分析、并参照血清CA125对 卵巢肿块的定性诊断有重要价值，能有 效提高鉴别诊断水平。

Objective To investigate the value of MRI, DWI and serum CA125 in qualitative diagnosis of ovarian tumors. Methods Collected MRI and clinical data of 76 patients with ovarian tumors.All cases underwent MR imaging including sagittal T2WI, axial T1WI and T2WI with fat satturation, DWI sequence(b=50,500, 800s/mm2 ) at 1.5 T Siemens MR scanner. In Siemens post-processing workstation analysis of signal characteristics of ovarian tumors, benign and malignant solid tumor measurement part of the ADC values. Results There was a significant difference(P<0.05) between the ADC value comparison about solid parts of ovarian benign (not teratoma)and malignant tumor, the area under the ROC curve for 0.904, the best diagnostic threshold for 1.281×10-3 mm2 /s.In The MRI diagnosis ,the sensitivity, specificity,Youden index and the Kappa value were 80.0%, 92.2%, 72.2% and 0.729, in the MRI combined with serum CA125 diagnosis, the sensitivity, specificity. Youden index and the Kappa value were 88.0%, 94.1%, 82.1% and 0.821. Conclusion The conventional MRI combined with ADC values, and serum CA125 in qualitative diagnosis of ovarian tumor has an important value, can effectively improve the level of differential diagnosis.