摘要
目 的 比较分析多层螺旋 CT(MSCT)、MRI对胰腺癌的诊断价值。方 法 对本院2013年4月-2015年6月60例临 床怀疑胰腺癌患者的MSCT、MRI影像学资 料进行回顾性分析,以手术病理结果为 对照,比较MSCT、MRI对胰腺癌诊断敏感 度、特异度、准确度,及对胰腺癌早期分 期确诊率。结果 手术病理证实胰腺癌38 例,MSCT诊断胰腺癌敏感度84.2%,特异 度77.3%,准确率81.75,较MRI的92.1%、 72.7%、85.0%差异无统计学意义(P> 0.05)。CT、MRI对早期胰腺癌确诊率比较 差异也无统计学意义(P>0.05)。胰腺癌 在CT图像上表现出胰腺肿大、形态不规则 特点,增强扫描可见胰腺实质内低密度 肿块;胰腺癌MRI呈T1WI低或略低信号、 T2WI混杂或略高信号特点。结论 MRI相比 MSCT对胰腺癌诊断敏感度、准确度略高, 而MSCT诊断特异度略高,各有优势,需根 据患者情况选择合理影像学手段。
Objective To compare and analyze the value of multi-slice spiral CT (MSCT) and MRI in the diagnosis of pancreatic cancer. Methods The MSCT and MRI data of 60 cases of patients with suspected pancreatic cancer who admitted in our hospital between April 2013 and June 2015 were analyzed retrospectively. With pathological results as control, the sensitivities, specificities and accuracies of MSCT and MRI in the diagnosis of pancreatic cancer and the diagnosis rate of early pancreatic staging were compared. Results Surgery and pathology confirmed 38 cases with pancreatic cancer. The sensitivity, specificity and accuracy of MSCT in the diagnosis of pancreatic cancer were 84.2%, 77.3% and 81.75, respectively. Compared with those of MRI (92.1%, 72.7%, 85%), there was no significant difference (P>0.05). There were no significant differences in diagnosis rate of early pancreatic cancer between CT and MRI (P>0.05). CT images of pancreatic cancer showed pancreatic enlargement and irregular shape. Enhanced scan showed low-density masses in the pancreatic parenchyma; MRI images of pancreatic cancer showed low or slightly low signal on mass T1WI, mixed or slightly low signal on T2WI. Conclusion Compared with MSCT, the sensitivity and accuracy of MRI in diagnosis of pancreatic cancer are slightly higher while the specificity of MSCT is slightly higher. Both if the two diagnostic methods have their own advantages. Therefore, appropriate imaging method should be chosen according to the real condition of patients.
【关键词】胰腺癌;多层螺旋CT;MRI; 诊断准确度
【中图分类号】R814.42;R735.9
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2016.08.002
前言
胰腺癌恶性程度高,由于其早期无明显临床症状、且无特异性, 临床确诊时多为中晚期,多失去手术机会。据报道,胰腺癌5年存活 率<5%,即使手术切除其5年存活率也<20%[1],但对肿瘤直径<1cm患 者来说,及时行以手术切除为主的综合治疗其5年存活率高达100%[2], 故早期诊断胰腺癌具有十分重要的意义。近年来超声、多层螺旋 CT(MSCT)、MRI等影像学方法在胰腺癌诊断中应用较多,通过对病灶直 径、位置、性质、病灶与周边组织及血管关系等全面反映以诊断或鉴 别胰腺癌,为临床治疗方案制定、预后评估提供重要依据[3]。本研究 通过与手术病理结果对照,比较分析MSCT、MRI对胰腺癌的诊断价值。 报告如下。
中国CT和MRI杂志
第14卷, 第 8 期
2016年08月
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