目的 总结乳腺癌患者E-cad表达 对MRI影像特点的影响。方法 选取我院 2012年3月-2015年12月收治86例乳腺癌 患者为例，均行MRI、免疫组化检查，比 较E-cad阳性及阴性患者MRI影像表现的差 异。结果 60例E-cad阳性表达患者中，16 例(26.7%)形状为类圆形、60.0%(36/60) 边缘为光滑或毛刺、36.7%(22/60)为均匀 与环形强化、48.3%(29/60)为TIC I型与 Ⅱ型曲线，所占比例均高于E-cad阴性表 达患者，差异有统计学意义(P﹤0.05)。结 论 乳腺癌患者E-cad阳性表达者形状多 为类圆形、边缘光滑或有毛刺、均匀或环 形强化，TIC曲线以I型与Ⅱ型居多，影 像表现与E-cad阴性表达患者存在较大差 异。

Objective To summarize the effect of E-cad expression on MRI imaging characteristics of breast cancer patients. Methods A total of 86 cases of patients with breast cancer who were treated in our hospital between March 2012 and December 2015 were selected as subjects. All patients were examined by MRI and immunohistochemistry. The differences of MRI findings between positive and negative expression of E-cad were analyzed. Results Among the findings of 60 patients with positive expression of E-cad, 16 cases (26.7%) showed quasi-circular shape, 60% (36/60) showed smooth or burr edges, 36.7% (22/60) showed homogeneous and ring enhancement and 48.3% (29/60) showed TIC I and II type curve. The proportions were higher than those in patients with negative expression of E-cad (P<0.05). Conclusion The findings of patients with breast cancer and positive expression of E-cad are quasi-circular, with smooth or burr edges, homogeneous or ring enhancement. The major curves are type I and II. The imaging findings are significantly different from those of patients with negative expression of E-cad.