论著-头颈部
CT肝脏体积测量技 术在肝硬化患者肝 脏功能Child-Pugh 分级中的应用研究*
作者:王晓伟1 贺安平2
所属单位:1.河南省安阳市第五人民医院九科 (河南 安阳 455000) 2.郑州大学第一附属医院影像科 (河南 郑州 450052)
PDF摘要
目的 探讨CT肝脏体积测量技术 在肝硬化患者肝脏功能Child-Pugh分级中 的应用价值。方法 将2012/5至2015/5来 我院进行检查并确诊的85例肝硬化患者纳 入本研究,按照患者肝脏功能Child-Pugh 分级分为A级组30例、B级组29例和C级组 26例。选取同期我院体检中心体检的60例 健康人作为对照组。4组入选者均进行CT 肝脏扫描,比较肝硬化组患者与对照组肝 脏各区域体积、不同Child-Pugh分级肝硬 化患者肝脏体积以及健康人不同年龄肝脏 体积差异。结果 肝硬化组患者左外叶和 尾叶体积明显高于对照组,左內叶、右前 叶、右后叶及总体积均明显低于对照组, 有统计学差异(P<0.05);肝硬化患者随 着Child-Pugh分级升高肝脏体积呈明显递 减趋势,三组间对比,有统计学差异(P <0.05);对照组随年龄增长肝脏体积呈 明显递减趋势,三组间对比,有统计学差 异(P<0.05)。结论 肝硬化患者肝脏体积 缩小程度与Child-Pugh分级呈负相关,CT 肝脏体积测量对患者肝脏功能Child-Pugh 分级具有重要参考价值。
Objective To explore the application on the liver function Child-Pugh classification for the patients with cirrhosis of liver by CT liver volume measurement techniques. Methods 85 cases of patients with cirrhosis of liver were divided into group A(30 cases), group B(29 cases) and group C(26 cases) according to liver function ChildPugh classification. 60 cases of healthy person were researched as the control group. The volume in each region of the liver, different Child - Pugh, hierarchical volume in patients with liver cirrhosis, healthy liver volume difference between different age were compared. Results The left lateral external lobe of liver, caudate lobe for the patients with cirrhosis of liver were higher than the control group(P<0.05). The left lobe, right anterior lobe, right rear leaf and total volume for the patients with cirrhosis of liver were lower than the control group(P<0.05). The Child - Pugh, classification of patients with liver cirrhosis liver volume was significantly decreasing trend(P<0.05); The liver volume was significantly decreasing trend along with the age growth(P<0.05). Conclusion It negative correlations patients with cirrhosis liver volume shrink degree and Child-Pugh, it has important reference value CT of the liver volume measurement of liver function in patients with Child-Pugh.
【关键词】肝硬化;CT肝脏体积测量; Child-Pugh分级
【中图分类号】R657.3+1
【文献标识码】A
【DOI】10.3969/j.issn.1672- 5131.2016.08.011
前言
肝脏是人体重要的新陈代谢器官,随着近几年肝脏疾病发病率的 不断增长,肝硬化的影像学诊断和病情评估越来越引起人们的关注。 肝硬化起病比较隐匿,早期多数患者不会出现典型症状,随着病情 进展肝脏会发生明显的形态学改变[1]。大量国内文献报道指出,肝硬 化患者肝脏体积与肝功能分级有紧密联系,肝脏体积测量在肝功能 Child-Pugh分级与预测手术切除体积方面均有重要价值[2]。本院通过 对健康人与肝硬化患者CT肝脏体积测量结果进行分析,以期明确肝硬 化患者肝脏体积变化规律以及CT肝脏体积测量技术的临床价值,现报 告如下。
中国CT和MRI杂志
第14卷, 第 8 期
2016年08月
相关文章