论著-头颈部
DWI在宫颈癌诊断及预后检测的价值*
作者:梁真娇1 梁梅芬1 钟菀杞1 董延江2 周雁玲2 余艳萍1 王永莉1
所属单位:1.南方医科大学附属小榄医院妇产 科 (广东 中山 528415) 2.南方医科大学附属小榄医院放射 科 (广东 中山 528415)
PDF摘要
目的 探讨DWI在宫颈癌诊断及 预后检测的价值。方法 选择我院2011 年1月至2014年1月收治的100例宫颈癌患 者。同期选择100例宫颈癌放疗后患者及 100例健康体检者,对表观扩散系数值 进行分析。结果 与正常宫颈管腺体相 比,宫颈纤维间质的表观扩散系数值为 1.70±0.45×10-3mm2 /s,对比分析后,差 异有统计学意义(t=6.834,P<0.05)。 100例宫颈癌病灶在DWI均呈现高信号状 态。根据患者侵犯深度,低信号的宫颈纤 维间质将会出现消失。与正常宫颈对比分 析后,宫颈癌患者的表观扩散系数值为 1.02±0.32×10-3mm2 /s,对比分析后,差 异有统计学意义(t=12.412,P<0.05)。 与宫颈癌患者相比,预后恢复正常患者 的表观扩散系数值为1.45±0.41×10- 3 mm2 /s,对比分析后,差异有统计学意义 (t=7.395,P<0.05)。与初诊宫颈癌患者 相比,宫颈癌复发患者的表观扩散系数值 为0.82±0.20×10-3mm2 /s,对比分析后, 差异有统计学意义(t=8.295,P<0.05)。 结论 DWI能够显著的辨别正常宫颈及宫颈 癌疾病,同时还能够显著地观察到放疗后 宫颈组织变化,对宫颈癌的诊断及预后具 有重要的价值。
Objective To investigate the diagnosis and prognosis value of DWI in detecting cervical cancer. Methods 100 patients with cervical cancer were selected from January 2011 to January 2014. 100 cases of cervical cancer radiotherapy troubles and 100 cases of healthy patients were also closed.The apparent diffusion coefficient were analyzed. Results Compared with normal cervical glands, the apparent diffusion coefficient values of cervical fibrous was 1.70±0.45×10-3mm2 /s, after comparative analysis, the difference was statistically significant (t=6.834,P<0.05). 100 cases of cervical lesions in DWI showed high signal state. According to the depth of patient invasion, the low signal of cervical fiber disappeared. Compared with normal cervix, the apparent diffusion coefficient value of cervical cancer patients was 1.02±0.32×10-3mm2 /s, after comparative analysis, the difference was statistically significant (t=12.412,P<0.05). Compared with patients with cervical cancer, the prognosis of patients with normal apparent diffusion coefficient value was 1.45±0.41×10-3mm2 /s, after comparative analysis, the difference was statistically significant (t=7.395,P<0.05). Compared with newly diagnosed with cervical cancer, cervical cancer recurrence in patients with apparent diffusion coefficient value was 0.82± 0.20×10-3mm2 /s, after comparative analysis, the difference was statistically significant (t= 8.295, P<0.05). Conclusion DWI approach can significantly distinguish normal cervix and cervical disease and it also being able to significantly observe human cervical tissue changes after radiotherapy.
【关键词】DWI;宫颈癌;表观扩散系数
【中图分类号】R445.2;R737.3
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2016.01.033
前言
宫颈癌疾病是一种危害极大的恶性肿瘤[1,2]。对患者进行早期诊断 是患者进行有效治疗重中之重。MRI检查方式在宫颈癌分期中已经逐渐 获得了关注,随着医学技术的发展,弥散加权成像(DWI)技术对于妇科 肿瘤疾病的应用也越来越多[3,4]。本研究中,采取宫颈癌扩散加权成像 (DWI)技术进行分析,探讨其应用价值,现报告如下。
中国CT和MRI杂志
第14卷, 第 1 期
2016年01月
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