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CT与MRI诊断前列腺癌的临床价值分析

作者:尚柳彤1 王婷婷2

所属单位:1.中国人民解放军总医院第一附属 医院核磁室 (北京 100073) 2.新疆医科大学公共卫生学院儿少 卫生教研室 (新疆 乌鲁木齐 830054)

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摘要

目的 研究CT和MRI对前列腺癌的 临床诊断价值,为提高临床诊断率提供 理论依据。方法 选择对比研究的方式对 2013年12月-2014年12月70例前列腺癌患 者展开研究,所有患者均行CT检查(对照 组)和MRI检查(研究组),并以病理组织诊 断结果为标准对两种检查方式进行优劣的 比较。结果 以病理活检为标准,在前列 腺癌A期和B期患者的诊断中,两组患者在 诊断相符率、误诊率及漏诊率的比较上 χ2 =40.17、17.69、12.99,P<0.05,具 有明显统计学差异;在前列腺癌C期和D期 患者的诊断中,两组患者无明显差异。结 论 MRI对前列腺癌的诊断准确率高,可作 为对患者进行分期评估的临床辅助检查方 式进行推广;CT对前列腺癌患者的A期和B 期诊断率低,仅在C期和D期的诊断中具有 较高的准确率,因此不建议在早期前列腺 癌的诊断中使用。

Objective This paper is to investigate clinical value of CT and MRI in diagnosis of prostate cancer, and to provide theoretical basis for improving clinical diagnostic rate. Methods The method of comparative study was applied to conduct investigation on 70 patients with prostate cancer from December, 2013 to December, 2014, all patients underwet CT examination (control group) and MRI (research group), and advantages and disadvantages of two types of inspection method were compared on the basis of histopathologic diagnosis. Results The comparisons in consistent diagnosis rate, misdiagnosis rate and the rate of missed diagnosis of patients in two groups in the diagnosis of prostate cancer of patients at Stage A and Stage B on the basis of pathological biopsy satisfied χ2 =40.17, 17.69 and 12.99 (P<0.05) respectively, the differences were significantly statistical, and there was no difference between the two groups of patients in the diagnosis of patients with prostate cancer at stage C and D. Conclusions MRI delivers high accuracy in the diagnosis of prostate cancer, and it can be used and promoted in auxiliary examination of clinical evaluation on patients in stages way, CT casts diagnostic rate of patients with prostate cancer at Stage A and Stage B, and high accuracy is only founded in the diagnosis at Stage C and Stage D, therefore it is not recommended to be used in the diagnosis of early prostate cancer.

【关键词】CT;MRI;前列腺癌;临床价值

【中图分类号】R445.2;R737.2

【文献标识码】A

【DOI】10.3969/j.issn.1672- 5131.2016.01.030

前言

前列腺癌属于雄性激素依赖性恶性肿瘤性质的病症,多发于高龄 男性[1]。随着生活水平的提高,发病率呈现出逐年上升的趋势。目前 对前列腺癌的发病因素尚未完全明了,针对病因进行治疗仍处于实验 阶段,不具备在临床大规模应用的条件,故适宜的诊断方式对前列腺 癌的早期诊断是泌尿外科医师研究的主要方向。现如今临床较常使 用的包含前列腺特异性抗原检查、直肠指诊、CT、核素骨显像B超、 MRI、前列腺穿刺活检等,但具有程度不一的临床诊断特异性和灵敏性 [2]。为探究CT与MRI对前列腺癌的临床诊断价值,笔者对70例前列腺癌 患者分别采用CT和MRI检查,并以手术病理组织诊断为标准对两种检查 方式进行评价,现将方法和结果展述如下。