目的 探讨彩色多普勒超声在肾 脏弥漫性病变诊断中的价值。方法 收集 2013年6月至2014年6月于我院接受彩色多 普勒超声检查的肾脏弥漫性病变患者80 例，其中42例为急性肾病患者(急性组)， 另38例为慢性肾病患者(慢性组)，另选择 同期健康体检者20例作为对照组，检测三 组受试者肾功能指标血清尿素氮(BUN)以 及尿肌酐(Cr)，对三组受试者行彩色多普 勒超声检查，对比观察三组患者肾脏大 小和肾皮质厚度，超声参数包括叶间动 脉收缩期峰值流速(Vmax)、叶间动脉阻 力指数(RI)和段动脉加速时间(AT)。结 果 三组BUN和Cr比较差异有统计学意义 (均P＜0.05)，急性组显著高于慢性组和 对照组(均P＜0.05)，慢性组显著高于对 照组(P＜0.05)；三组肾脏长、宽、厚和 肾皮质厚度比较差异均有统计学意义(均P ＜0.05)，其中急性组肾脏长、宽、厚和 肾皮质厚度显著高于慢性组和对照组(均P ＜0.05)，慢性组肾脏长、宽、厚和肾皮 质厚度显著低于对照组(P＜0.05)；三组 叶间动脉Vmax、叶间动脉RI和段动脉AT比 较差异均有统计学意义(均P＜0.05)，其 中急性组叶间动脉Vmax显著高于对照组和 慢性组，而慢性组显著低于对照组，差异 均有统计学意义(均P＜0.05)；急性组叶 间动脉RI、段动脉AT显著低于对照组和慢 性组，而慢性组显著高于对照组，差异均 有统计学意义(均P＜0.05)。结论 肾脏弥 漫性病变患者肾脏大小和肾皮质厚度均表 现出一定程度的升高或降低，彩色多普勒 超声技术可有效协助临床对肾脏慢性弥漫 性患者的诊断、治疗及预后评估，且检查 方法安全可靠、简便易行，无创伤，值得 临床推广及应用。

Objective To study the value of Color Doppler ultrasound in the diagnosis of renal diffuse lesions. Methods 80 cases of diffuse lesions collected from 2013 June to 2014 June in my hospital underwent color Doppler ultrasonography of the kidney, including 42 cases of acute kidney disease patients (the acute group), another 38 cases of patients with chronic kidney disease (the chronic group), to explore the clinical value of color Doppler ultrasound in the diagnosis of renal diffuse lesions. Results There was statistically significant difference of BUN and Cr among the three groups(all P<0.05),acute group was significantly higher than chronic group and the control groups(all P<0.05),chronic group was significantly higher than that of control group (P<0.05);There was statistically significant difference of the length, width, thickness of kidney and renal cortical thickness among the three groups(all P<0.05),acute group was significantly higher than chronic group and the control groups(all P<0.05),chronic group was significantly lower than that of control group (P<0.05);There was statistically significant difference of Artery Vmax,RI and segment artery AT among the three groups(all P<0.05),arterial Vmax in acute group was significantly higher than chronic group and the control groups(all P<0.05),chronic group was significantly lower than that of control group (P<0.05);RI and segment artery AT in acute group was significantly lower than chronic group and the control groups(all P<0.05),chronic group was significantly higher than that of control group (P<0.05). Conclusion Color Doppler ultrasound technology can effectively assist clinical on renal chronic diffuse diagnosis, treatment and evaluation of prognosis of patients, and check method is safe and reliable, simple, non-invasive, is worth the clinical promotion and application